C-Trap installation at B CUBE TU DresdenUncategorised

Second C-Trap™ installed in Dresden, Germany

The city of Dresden, Germany, is now the home of two C-Trap® systems! The latest installation took place at the Center for Molecular and Cellular Bioengineering at TU Dresden, where the instrument became part of the Joint Technology Platform. Being operated in the "Molecular Imaging and Manipulation" facility, the system will be available to multiple…
Doenja Jansen
26 March 2019
Uncategorised

New insights into Cas9 off-target activity

The paper “DNA stretching induces Cas9 off-target binding and cleavage” was just published in Nature Structural and Molecular Biology. Congratulations to all the authors! In this paper, scientists at the MRC London Institute of Medical Sciences and AstraZeneca studied how CRISPR-Cas9 differentiates between on-targets and off-targets. They used the C-Trap®…
C-Trap m-Trap 2019 Brochure CoversUncategorised

Step into the unresolved with the Surface Assay Toolkit

During BPS19, we introduced the Surface Assay Toolkit! A unique assortment of new features that enable scientists to investigate the cytoskeleton from a whole new dynamic perspective. The Surface Assay Toolkit brings together the C-Trap™ and m-Trap™ optical tweezers with:  Label-free surface imaging using IRM;  Rapid fluorescent imaging in solution using Widefield;  Fluorescence surface imaging using TIRF;  High throughput experimental workflow at the surface. Download the 2019…
Doenja Jansen
7 March 2019
New C-Trap® Installed at the University at BuffaloUncategorised

New insights on the formation and dynamics of membraneless organelles using C-Trap™

Congratulations to Dr. Priya R. Banerjee and his research group at University at Buffalo, who just published their paper in Biomolecules! In the paper titled “Molecular crowding tunes material states of ribonucleoprotein condensates” they investigated how entropic forces contribute to the formation and dynamics of membraneless organelles. Using their C-Trap…
Kassandra Barbetsea
28 February 2019
C-Trap Installation at UC MercedUncategorised

C-Trap™ installed at UC Merced

A C-Trap™, optical tweezers coupled with fluorescence microscopy, has been successfully installed at the University of California, Merced. The system is shared by the research groups of Prof. Eva de Alba and Prof. Victor Muñoz. Their labs focus on the study of proteins, which are involved in almost all cellular processes. This makes the…
Jerom Langeveld
18 February 2019
Blog posts

C-Trap installed at TU Delft

We are thrilled about the recent C-Trap® installation in the Department of Bionanoscience at the TU Delft, one of the leading universities in The Netherlands! The groups of Prof. Nynke Dekker and Prof. Marileen Dogterom will use the C-Trap to study the dynamic aspects of DNA replication and cytoskeleton-based processes,…
Jerom Langeveld
13 December 2018
phase separation IDP researchUncategorised

New C-Trap™ Installed at the University at Buffalo

LUMICKS successfully installed a C-Trap® optical tweezers–fluorescence microscopy system in the lab of Assistant Professor Priya Banerjee at the University at Buffalo. The group of Dr. Banerjee will use the C-Trap to investigate the structural dynamics and phase behavior of intrinsically disordered proteins (IDPs). IDPs are characterized by conformational plasticity and structural heterogeneity,…
Jerom Langeveld
17 October 2018
Single-Molecule Workshop at the University of CambridgeUncategorised

Single-Molecule Workshop at the University of Cambridge

An engaging single-molecule workshop organized by LUMICKS took place at the University of Cambridge. During the workshop, the participants performed state-of-the-art experiments to examine DNA-protein interactions and DNA mechanics in real-time and at the single-molecule level, using the C-Trap® optical tweezers - fluorescence microscopy system. Next to the practical sessions, Matt Newton, a researcher from…
Jerom Langeveld
2 October 2018

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