Researchers use the m-Trap® and C-Trap® to discover CRISPR-Cas9 properties that can help improve in vivo efficiency

A recent publication from the research lab of Dr. Bo Sun presents new findings in the field of gene editing that may help improve in vivo delivery of CRISPR-Cas9 complexes. The team investigated the DNA-binding properties of Staphylococcus aureus Cas9 … Continue Reading

Study finds essential Cas9–DNA interaction downstream of PAM using a single-molecule approach

A new publication shows how the lab of Dr. Bo Sun used the m-Trap® to analyze the interactions between a Cas9–gRNA complex and DNA. Using a single-molecule approach to unzip the target double-stranded DNA, the team showed interaction points on the … Continue Reading

New application note shows how to study Cas9 target specificity at the single-molecule level using the C-Trap™

We are happy to announce that our application note Analyze Cas9 Binding and Cleavage Properties in Real Time while Manipulating DNA Structures is available to download on our website. In this application note, you can learn how the group of … Continue Reading