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C-Trap Archives - Page 11 of 11 - LUMICKS

DNA-repair-NatureUncategorised

Paper Using LUMICKS Technology Published in Nature

Great news: Another paper using LUMICKS technology was published, this time in Nature! Congratulations to the authors. Several are now part of LUMICKS. In the study “Sliding sleeves of XRCC4-XLF bridge DNA and connect fragments of broken DNA” Brouwer et al. describe how XRCC4 and XLF proteins play a crucial role…
Jerom Langeveld
21 July 2016
optical-tweezers-fluorescence-microscopy-Nature-CommunicationsUncategorised

Study using CTFM Published in Nature Communications

A new paper using the correlative optical tweezers-fluorescence microscopy (CTFM) technology has recently been published in Nature Communications. King, Peterman & Wuite show in "Unravelling the structural plasticity of stretched DNA under torsional constraint" that in torsionally constraint DNA concomitant basepair melting and helical unwinding can occur at forces >~50…
Jerom Langeveld
15 June 2016
optical-tweezers-workshopUncategorised

CTFM Workshop at BIOCEV a Great Success

The latest workshop on correlative optical tweezers and fluorescence microscopy (CTFM) was a great success. On June 8 and 9 the participants joined the hands-on workshop and were updated on the latest developments on CTFM at BIOCEV in Prague. Interested in attending the next workshop? Register now on our workshop…
Jerom Langeveld
10 June 2016
optical-tweezers-fluorescence-microscopy-BIOCEV-PragueUncategorised

LUMICKS Delivers C-Trap™ to BIOCEV Prague

In January 2016 LUMICKS installed a C-Trap™ Correlative Optical Tweezers Fluorescence microscope at the BIOCEV Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University in Vestec. Acquired by the research group of Dr. Zdeněk Lánský, the C-Trap™ is used to study molecular motors and structural proteins that…
Jerom Langeveld
14 February 2016
Uncategorised

CTFM Appears in Bionews

LUMICKS’ technology was featured in the Dutch journal Bionews, with articles on how the C-Trap™’s Correlative Tweezers-Fluorenscence Technology revealed that the working of the RAD51 protein in the DNA repair process takes place independent of BRCA2 proteins. This contrary to earlier models on BRCA2’s role in this process and the…
Jerom Langeveld
15 October 2014
Uncategorised

CTFM Results on RAD51 Appear in PNAS

In a recent publication, Correlative Tweezers-Fluorescence Microscopy was used to reveal a fundamental step in one of the most crucial biological process that occur in a cell: DNA repair. The article appeared in the renowned journal PNAS, and was portrayed on the Dutch newspaper Bionieuws. In their work, VU researchers…
Jerom Langeveld
6 October 2014
Uncategorised

VU Group Receives ERC Proof of Concept Grant

The group of Prof. Gijs Wuite and Prof. Erwin Peterman at the VU University Amsterdam received an ERC Proof of Concept grant to do a market study and product feasibility study for the recently developed single-molecule experimentation instrument of optical tweezers integrated with confocal fluorescence microscopy and a laminar flow…
Jerom Langeveld
1 December 2013