Explore the z-Movi Cell Avidity analyzer

Meet z-Movi: the only technology that enables you to
find the most potent immune cells and quantify their
binding strength to their target.

T cell

functionality

A new predictor of

Discover the teams of Dr. Eric Smith (Dana-Farber Cancer Institute) and Prof. Carlos de Larrea (Hospital Clínic Barcelona) used the z-Movi to predict CAR T-cell efficacies that correlate with treatment outcomes in vivo.

Application Note Now Online

Rapidly identify new, effective CAR T-cell therapy candidates for multiple myeloma through cell-avidity measurements. 

Download
Explore the z-Movi

Meet z-Movi: the only technology that enables you to find the most potent immune cells and quantify their binding strength to their target.

A new predictor of
T cell functionality

Download

Application Note Now Online

 

Rapidly assess
CAR T-cell strategies 

Discover LUMICKS

LUMICKS is the leading supplier of Dynamic Single-Molecule and Cell Avidity analysis instruments. Our instruments enable – for the first time – the analysis of complex dynamic details related to the behavior and interaction of single molecules and cells. 

Built upon innovative and Nobel Prize-winning technologies, such as optical tweezers (Nobel Prize for Physics 2018), and STED super-resolution (Nobel Prize for Chemistry 2014), our tools enable the understanding of life to the smallest detail.

Our goal is to improve human health by unlocking the power of Dynamic Single-Molecule and Cell Avidity analysis to provide unparalleled insight into the fundamental cause of disease and potential for drug optimization. These technologies are rapidly evolving as a mainstream approach in academic and pharma research for the study of DNA–protein interactions, molecular motor activity, protein folding, and cell–cell interactions.

Want to see your favorite biomolecules or cells in action?  Contact  us for a demo!

Applications

DNA/RNA-protein Interactions
Protein folding and conformational changes
Cellular structure and transport
Protein droplets and phase separation
Drug research
Immuno-oncology

Products

C-Trap®

Optical Tweezers – Fluorescence & Label-free Microscopy

The C-Trap® is the world’s first instrument that combines high resolution optical tweezers, fluorescence and label-free microscopy with an advanced microfluidics system in a truly integrated and correlated solution.

m-Trap®

Optical Tweezers

The m-Trap® optical tweezers was developed to lower the price barrier of advanced single-molecule force spectroscopy instrumentation without compromising on performance. It combines high force resolution and stability, with incredible throughput, ease of use and modularity.

AFS®

Parallel Single-molecule Force Spectroscopy

Acoustic Force Spectroscopy, or AFS®, is LUMICKS’ highly parallel single-molecule manipulation method capable of applying controlled forces on hundreds of biomolecules or cells in parallel.

u-Flux™

Laminar Flow Microfluidics

The u-Flux™ microfluidics system is an integrated solution to reliably perform single-molecule experiments in a laminar flow environment. The system consists of a laminar flow cell, a highly stable passive pressure system and multiple fluidic valves.

z-Movi®

Cell Avidity Analyzer

z-Movi®  offers you a fast and simple alternative to optimize and select immunotherapeutic strategies in a highly predictive and reproducible manner. By directly measuring cell avidity, the z-Movi provides you with reliable results in no-time.