Implement optical tweezers to evaluate the highly dynamic and transient protein droplets and to understand how and when these structures dissolve and form. You can apply the instrument to trap micron-sized particles, such as protein droplets or beads, with highly focused laser beams. Control the position of the trapped structure by regulating the direction and force of the beam.
Correlating the optical tweezers with fluorescence microscopy enables you to follow the trapped structures as you manipulate and measure droplet fusion or viscosity. Use the optical tweezers – fluorescence microscopy to study protein droplet properties in different conditions:
- Apply external forces to control the fusion between two protein droplets. Simultaneously follow and time the process through the multi-color fluorescence microscopy.
- Measure droplet stiffness and viscous drag in different conditions by bringing two polystyrene beads into adhesive contact with the droplet and deforming the droplet through controlled bead movements.
- Control and navigate your desired reagents and their concentrations through the barrierless, multichannel microfluidics system.