DNA-protein interactions (DPI) Archives

Blog posts

The C-Trap uncovers new insights into the mechanisms for ATP-dependent chromatin remodeling

PICH (Plk1-interacting checkpoint helicase) belongs to the SNF2 family of ATP-dependent chromatin remodelers. However, what makes PICH unique is that it lacks a nucleotide-binding domain despite having a great affinity for bare DNA. Because of this molecular structure, it has been hypothesized that the binding of PICH to chromatinized bridges…

Chenlu Yu13 June 2023

Blog posts

C-Trap^® experiments reveal novel mechanism for transcription termination in bacteria

New insights into the regulation of transcription termination have been revealed by researchers from the lab of Shixin Liu at The Rockefeller University, New York, in a recent publication in Molecular Cell. Using the powerful LUMICKS C-Trap® technology that allows the direct observation of molecular mechanisms, they were able to…

Chenlu Yu31 March 2023

Blog posts

C-Trap^® experiments shed light on the mechanisms that govern Structural Maintenance of Chromosome (SMC) Complexes

In two recent scientific publications, Johannes Stigler and his team from the Gene Center of the Ludwig-Maximilians-University Munich, Germany, set out to mechanistically describe the action of the Structural Maintenance of Chromosome (SMC) Complexes using LUMICKS’ C-Trap® technology. By performing dynamic single-molecule experiments coupled with real-time visualization, they were able…

Chenlu Yu9 March 2023

C-Trap reveals mechanism of protein-DNA co-condensate formation.

Blog posts

C-Trap^® experiments reveal mechanism of protein-DNA co-condensate formation

In a recent publication in PNAS, researchers from the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) and the Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) shed light on how proteins interact with individual DNA molecules to form co-condensates. Using LUMICKS’ C-Trap®, which combines optical tweezers, confocal microscopy, and…

Chenlu Yu16 March 2022

Blog posts

C-Trap^® experiments reveal how a pioneer transcription factor interacts with DNA to regulate gene expression

Researchers from the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany, led by Stephan W. Grill, have shed light on the physical nature of the interaction between the pioneer transcription factor Klf4 (Krüppel-like factor 4) and DNA. Using the C-Trap®, which combines optical tweezers, confocal microscopy…

Chenlu Yu23 February 2022

Blog posts

Newly formed Center for Optical Bio-Manipulation at the Niels Bohr Institute now equipped with an advanced C-Trap^® system

We’re overjoyed to announce the placement of one of our most sophisticated C-Trap® systems at the newly formed Center for Optical Bio-Manipulation (COBM) at the Niels Bohr Institute, University of Copenhagen! The center is based around LUMICKS' C-Trap system, flaunting quadruple optical tweezers, 3 color confocal fluorescence microscopy, and STED…

Adrià Ferragut13 July 2021

Blog posts

Advanced C-Trap^® systems recently installed at two universities in Europe

We are delighted to announce two new C-Trap® installations in Europe, one at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) and the other at the University of Kent. At MPI-CBG, this will be the second C-Trap installed. The new system is configured with quadruple optical traps…

Adrià Ferragut6 July 2021

Blog posts

Two Chinese universities now equipped with a C-Trap^® system

We are very pleased to announce two new C-Trap® installations in China, one at the Microscopy Core Facility at Westlake University and one at the Institute of Advanced Studies at Soochow University. We begin with the group of Dr. Huizhong Xu at the Institute of Advanced Studies, Soochow University. Their…

Adrià Ferragut15 June 2021

Blog posts

Three C-Trap^® systems installed in the US East Coast

We are excited to share that three more institutes on the US East Coast are now equipped with a C-Trap® Optical Tweezers – Fluorescence Microscope! The three new instruments are now housed at a new core facility at MSKCC, at the NanoSystems Laboratory at the OSU, and at the UPMC-Hillman Cancer…

j.yeh17 May 2021

Top banner images were licensed by Jose Luis Stephens (Santiago de Chile) / Sean Pavone (Salt Lake City) / Boris Stroujko (Wurzburg) / f11photo (Tokyo) / Shutterstock.com

Blog posts

LUMICKS technologies installed all around the world

As turbulent 2020 was, we are happy to have managed to install various LUMICKS instruments all around the world. Our dynamic single-molecule instruments enable researchers to analyze complex dynamic details related to the behavior and interaction of single molecules. One of these installations is the newly installed C-Trap® system at the…

j.yeh23 February 2021

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DNA-protein interactions (DPI) Archives - LUMICKS

The C-Trap uncovers new insights into the mechanisms for ATP-dependent chromatin remodeling

C-Trap^® experiments reveal novel mechanism for transcription termination in bacteria

C-Trap^® experiments shed light on the mechanisms that govern Structural Maintenance of Chromosome (SMC) Complexes

C-Trap^® experiments reveal mechanism of protein-DNA co-condensate formation

C-Trap^® experiments reveal how a pioneer transcription factor interacts with DNA to regulate gene expression

Newly formed Center for Optical Bio-Manipulation at the Niels Bohr Institute now equipped with an advanced C-Trap^® system

Advanced C-Trap^® systems recently installed at two universities in Europe

Two Chinese universities now equipped with a C-Trap^® system

Three C-Trap^® systems installed in the US East Coast

LUMICKS technologies installed all around the world

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DNA-protein interactions (DPI) Archives - LUMICKS

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About LUMICKS

For pricing, reach out to your application scientist or account manager

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Download our Cell Therapy (CAR-T, TCR, NK) applications deck

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