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Motor Protein Application NoteBlog posts

Motor Protein Application Note Now Online

The cytoskeleton and its many molecular motors are major players in a variety of cellular functions. The interconnected networks of cytoskeletal filaments act as tracks directing molecular motor transport and provide structural support and organization to cells. One example of a class of motor proteins is the myosin superfamily, a…
Jerom Langeveld
10 January 2018
DNA BreathingBlog posts

DNA Breathing Application Note Now Online

DNA breathing, also known as fraying, describes the spontaneous local conformational transitions occurring within double-stranded DNA (dsDNA). Due to the transient and spontaneous nature of this process, the study of real-time DNA breathing transitions at the single-molecule level requires the use of highly sensitive experimentation technologies. Using LUMICKS’ high-resolution optical tweezers, small and transient DNA…
Jerom Langeveld
28 September 2017
BIOCEV customer case story - Academy of Sciences of the Czech Republic, Faculty of Science and the First Faculty of Medicine of the Charles University in PragueBlog posts

Customer Case Story BIOCEV Prague

In January 2016, LUMICKS’ first C-Trap® Optical Tweezers-Fluorescence Microscopy instrument was successfully installed at the BIOCEV research center in the Czech Republic. BIOCEV is a research institute in the areas of biotechnology and biomedicine of both the Academy of Sciences of the Czech Republic and the Charles University. The instrument…
Jerom Langeveld
13 September 2017
cytoskeleton filament manipulation using optical tweezers fluorescence microscopyBlog posts

Filament Manipulation Application Note Now Online

Protein filaments have been studied indirectly using various approaches of fluorescence microscopy in cells and tissues and more directly, using force spectroscopy on single filaments or filament bundles. LUMICKS' C-Trap® provides for a unique approach which combines the strength of both techniques, to give a truly correlative method of studying…
Jerom Langeveld
6 September 2017
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