Blog posts

C-Trap® experiments suggest tubulin lattice state dictates tau envelope formation

Tau is an intrinsically disordered microtubule-associated protein (MAP) that helps stabilize microtubules by forming an envelope around them. This stabilizing protein has been implicated in neurodegenerative diseases such as Alzheimer’s, where abnormal chemical changes promote detachment of tau from microtubules and the formation of long threads that eventually lead to…
Rozina Kardakaris
22 September 2022
Blog posts

The Scientist Magazine features z-Movi®;

We couldn't have put the essence of our z-Movi®; in better words than the author of this article in The Scientist: "Just as music pulls some folks to the dance floor while others remain stuck to their chairs, sound can now be used to pull some cells loose from their substrate while other cells…
Doenja Jansen
25 January 2019
z-Movi has been featured in ScienceBlog posts

z-Movi® featured in Science

Our latest product, the z-Movi®;, has been featured in the latest issue of the journal Science! The z-Movi uses acoustic force manipulation to query the interaction strengths of cells with their cognate binding partners. It is based on a lab-on-a-chip assay that allows the assessment of thousands of cell-cell and cell-ligand interactions…
Kassandra Barbetsea
5 December 2018
Uncategorised

LUMICKS Featured in Cambridge Independent

This week’s issue of Cambridge Independent featured an article about our partnership with AstraZeneca and the University of Cambridge! We are proud to see the field of dynamic single-molecule analysis reaching a new milestone once again. This brings us closer to our goal: improving human health by providing unparalleled insight…
Jerom Langeveld
23 July 2018
optical tweezers dna repair force extension manipulation visualization RAD51 RecombinationUncategorised

Investigation of the Interaction of RAD51 with ssDNA Using CTFM and X-ray Crystallography

Recently, the paper “Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA" has been published in The EMBO Journal. Congratulations to Dr. Ineke Brouwer and all co-authors! Brouwer et al. combined Correlative Optical Tweezers-Fluorescence Microscopy (CTFM) with X-ray crystallography to investigate the function of human RAD51…
Jerom Langeveld
20 March 2018

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