Measure Cell Mechanics with Acoustic Force Spectroscopy

Novel Method for Single-Cell Mechanical Probing using LUMICKS’ AFS™ System

The article ‘Probing cellular mechanics with Acoustic Force Spectroscopy’ has recently been published in the journal Molecular Biology of the Cell. Congratulations to all the authors on their inspiring research! Undergoing deformations plays a vital role in the function of Red … Read More

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m-Trap™ installed at the Hong Kong University of Science and Technology

LUMICKS is proud to announce the installation of an m-Trap™ at the Hong Kong University of Science and Technology (HKUST) in the lab of Assistant Professor Jinqing Huang. Dr. Huang will be combining the m-Trap™ with Raman Spectroscopy to investigate … Read More

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Novel Insights on the Mechanical Properties of IFs using LUMICKS’ Technology

The journal Science Advances has recently published the paper ‘Viscoelastic properties of vimentin originate from nonequilibrium conformational changes’. We would like to congratulate Prof. Dr. Sarah Köster and all co-authors for their great work on intermediate filaments (IFs)! IFs are … Read More

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Single-Molecule Workshop at LUMICKS Amsterdam

During June 4-5, a captivating single-molecule workshop was given at the headquarters of LUMICKS in Amsterdam. Throughout the workshop, the participants were introduced to our second-generation (G2 line) apparatus and got the chance to perform multiple investigations on them. We … Read More

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C-Trap™ installed at Semmelweis University

LUMICKS is proud to announce the installation of a new C-Trap™ optical tweezers-fluorescence microscopy system in the lab of Professor Miklos Kellermayer at the Semmelweis University in Budapest, Hungary. A major focus of Prof. Kellermayer’s lab is in uncovering the molecular mechanics of the … Read More

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Single-Molecule Workshop at the Rockefeller University

A successful Single-molecule workshop took place on April 17 to 18 at the Rockefeller University in New York, organized by LUMICKS. During the practical hands-on workshop, the participants performed state-of-the-art single-molecule experiments to examine DNA mechanics, repair, and DNA molecular motors. They also attended demonstrations … Read More

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Single-Molecule Workshop at the ShanghaiTech University

On April 9 to 11, a successful Single-molecule workshop took place in the lab of Prof. Bo Sun at the ShanghaiTech University, organized by LUMICKS. During the practical hands-on workshop, the participants conducted state-of-the-art single-molecule experiments in the fields of DNA mechanics, … Read More

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Intercalated DNA

Method to Quantify Local Force Distribution within Biomolecular Systems

The journal Nano Letters has recently published the article “Quantifying Local Molecular Tension Using Intercalated DNA Fluorescence”. We would like to congratulate all the authors! By using optical tweezers coupled with fluorescence microscopy, Dr. King et al. (2018) studied the … Read More

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C-Trap™ installed in Bustamante Lab at UC Berkeley

LUMICKS recently installed a new C-Trap™ SR optical tweezers-STED nanoscopy system in the laboratory of Professor Carlos Bustamante at the University of California, Berkeley. The Bustamante Lab specializes in the development and application of novel single-molecule manipulation and detection methods. These methods are used to investigate the activity of individual molecular machines. Throughout his work, Prof. Bustamante has … Read More

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optical tweezers dna repair force extension manipulation visualization RAD51 Recombination

Investigation of the Interaction of RAD51 with ssDNA Using CTFM and X-ray Crystallography

Recently, the paper “Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA” has been published in The EMBO Journal. Congratulations to Dr. Ineke Brouwer and all co-authors! Brouwer et al. combined Correlative Optical Tweezers-Fluorescence Microscopy (CTFM) … Read More

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