News - LUMICKS

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C-Trap® experiments suggest tubulin lattice state dictates tau envelope formation

Tau is an intrinsically disordered microtubule-associated protein (MAP) that helps stabilize microtubules by forming an envelope around them. This stabilizing protein has been implicated in neurodegenerative diseases such as Alzheimer’s, where abnormal chemical changes promote detachment of tau from microtubules and the formation of long threads that eventually lead to…

Rozina Kardakaris22 September 2022

Blog posts

m-Trap® allows precise control of biological activities in synthetic membraneless organelles (MLOs) in real time

Until recently, the understanding of membraneless organelles (MLOs) was hindered by the inability to control their bioactivities in a precise manner. In a recent Nature Communications article from the lab of Huang and Sun, University of Hong Kong, researchers were able to overcome this obstacle by producing synthetic MLOs that…

Nelli Bossert23 August 2022

Blog posts

LUMICKS’ C-Trap^® adopted by two labs at UBC

We are delighted to announce the installation of two C-Trap® instruments at the University of British Columbia (UBC), Vancouver, Canada, in the labs of Dr. Derek Dee and Dr. Nada Lallous. Derek Dee, Assistant Professor in the Department of Land and Food Systems, focuses his research on the forces that…

Rozina Kardakaris14 July 2022

Blog posts

Dynamic single-molecule analysis reveals non-linear stiffening of mitotic chromosomes

In a recent study performed by Vrije Universiteit Amsterdam and the University of Copenhagen, researchers used LUMICKS’ u-Flux™ laminar flow microfluidics system together with optical tweezers and fluorescence microscopy – features combined in LUMICKS’ C-Trap® – to shed light on the structural organization of mitotic chromosomes. When preparing to undergo…

Rozina Kardakaris17 June 2022

“Avidity Enhancement” As New Strategy for Improving CAR T Therapy for AML

Press releases

Cancer Cell Paper Identifies “Avidity Enhancement” As New Strategy for Improving CAR T Therapy for Acute Myeloid Leukemia

The study details a novel strategy for better cancer treatment with CAR T cells for AML. "Avidity Enhancement", increasing cell-cell binding from both the tumor and CAR T cell side, led to a more effective eradication of tumors in mouse models of AML.

Maja Stephan24 May 2022

Blog posts

C-Trap^® studies reveal GroEL-ES protein folding acceleration mechanism

In a recent Science Advances publication, the group of Sander J. Tans from the AMOLF Institute, The Netherlands, demonstrate for the first time, at the single molecule level, how the molecular chaperone GroEL-ES modulates protein chain collapse and stimulates protein folding. Using LUMICKS’ C-Trap®, they were able to follow and visualize…

Rozina Kardakaris17 May 2022

Press releases

LUMICKS Appoints Andre Nel as Chief Financial Officer

We are very pleased to attract an experienced life sciences financial executive like Andre to LUMICKS at this pivotal point in our growth. His seasoned expertise across large, global life science companies, including Illumina and Pfizer, will be invaluable to us as we accelerate our growth worldwide.

Maja Stephan9 May 2022

Press releases

Nature Paper Identifies “Avidity Escape” as Solid Tumor Evasion Mechanism of CAR T Cell Cancer Therapies

In this study led by the team of Dr. Marcela Maus at Harvard Medical School, the LUMICKS z-Movi® Cell Avidity Analyzer showed that loss of interferon-γ receptor (IFNγR) signaling decreased cell binding avidity between CAR T cells and their target solid tumor cells.

Maja Stephan2 May 2022

Blog posts

New C-Trap^® installation at Radboud University to offer insights into chromatin organization

We are thrilled to announce the installation of a C-Trap® at the RIMLS-Science institute, Radboud University, The Netherlands, in the lab of Dr. Jorine Eeftens. The installed C-Trap combines dual-trap optical tweezers with super-resolution confocal microscopy, which will allow the team to perform and visualize single-molecule experiments with unprecedented detail to…

Rozina Kardakaris14 April 2022

Press releases

LUMICKS Strengthens its Innovative C-Trap^® Solution with Launch of New Lakeview Analysis Software Platform

With the release of the Lakeview Platform, we are bridging one of the biggest hurdles in our quest to democratize dynamic single-molecule instruments: straightforward data analysis that allows scientists to translate complex data sets to biologically relevant information

Maja Stephan4 April 2022

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C-Trap® experiments suggest tubulin lattice state dictates tau envelope formation

m-Trap® allows precise control of biological activities in synthetic membraneless organelles (MLOs) in real time

LUMICKS’ C-Trap^® adopted by two labs at UBC

Dynamic single-molecule analysis reveals non-linear stiffening of mitotic chromosomes

Cancer Cell Paper Identifies “Avidity Enhancement” As New Strategy for Improving CAR T Therapy for Acute Myeloid Leukemia

C-Trap^® studies reveal GroEL-ES protein folding acceleration mechanism

LUMICKS Appoints Andre Nel as Chief Financial Officer

Nature Paper Identifies “Avidity Escape” as Solid Tumor Evasion Mechanism of CAR T Cell Cancer Therapies

New C-Trap^® installation at Radboud University to offer insights into chromatin organization

LUMICKS Strengthens its Innovative C-Trap^® Solution with Launch of New Lakeview Analysis Software Platform

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