Single-Molecule Workshop at the Rockefeller University

A successful Single-molecule workshop took place on April 17 to 18 at the Rockefeller University in New York, organized by LUMICKS. During the practical hands-on workshop, the participants performed state-of-the-art single-molecule experiments to examine DNA mechanics, repair, and DNA molecular motors. They also attended demonstrations … Read More

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Single-Molecule Workshop at the ShanghaiTech University

On April 9 to 11, a successful Single-molecule workshop took place in the lab of Prof. Bo Sun at the ShanghaiTech University, organized by LUMICKS. During the practical hands-on workshop, the participants conducted state-of-the-art single-molecule experiments in the fields of DNA mechanics, … Read More

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Intercalated DNA

Method to Quantify Local Force Distribution within Biomolecular Systems

The journal Nano Letters has recently published the article “Quantifying Local Molecular Tension Using Intercalated DNA Fluorescence”. We would like to congratulate all the authors! By using optical tweezers coupled with fluorescence microscopy, Dr. King et al. (2018) studied the … Read More

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C-Trap™ installed in Bustamante Lab at UC Berkeley

LUMICKS recently installed a new C-Trap™ SR optical tweezers-STED nanoscopy system in the laboratory of Professor Carlos Bustamante at the University of California, Berkeley. The Bustamante Lab specializes in the development and application of novel single-molecule manipulation and detection methods. These methods are used to investigate the activity of individual molecular machines. Throughout his work, Prof. Bustamante has … Read More

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optical tweezers dna repair force extension manipulation visualization RAD51 Recombination

Investigation of the Interaction of RAD51 with ssDNA Using CTFM and X-ray Crystallography

Recently, the paper “Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA” has been published in The EMBO Journal. Congratulations to Dr. Ineke Brouwer and all co-authors! Brouwer et al. combined Correlative Optical Tweezers-Fluorescence Microscopy (CTFM) … Read More

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C-Trap™ installed at Ludwig Maximilian University

LUMICKS recently installed a new C-Trap™ system in the lab of Dr. Johannes Stigler at the Ludwig Maximilian University of Munich, Germany. Dr. Stigler and his group will use the C-Trap™ to study the structure and organization of chromosomes. Their goal is to determine the … Read More

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LUMICKS co-founding Professors G. Wuite & E. Peterman in the media after winning the NWO Physics Valorisation Prize 2017

After being awarded the NWO Physics Valorisation Prize 2017 for the valorization of their single-molecule research, Prof. Gijs Wuite and Prof. Erwin Peterman are featured in an article published in VU Magazine and an interview on a famous Dutch radio station (both … Read More

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AFS™ installed at Georgetown University

Last week, LUMICKS successfully installed an AFS™ Stand-Alone system in the lab of Assistant Professor Rodrigo Maillard at Georgetown University in Washington, D.C. They are experts in optical tweezers, which the group uses to probe and monitor the response of proteins upon force application in … Read More

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C-Trap AFS G2 Brochure cover

Introducing New Generation of Dynamic Single-Molecule Analysis Instruments

At the BPS18 meeting, LUMICKS will introduce its latest product generation of the C-Trap™ optical tweezers-fluorescence microscopy and AFS™ parallel single-molecule force spectroscopy instruments. The new G2 generation represents an evolution of our original instruments, bringing new enabling features, improved performance, and automation. These … Read More

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Motor Protein Application Note

Motor Protein Application Note Now Online

The cytoskeleton and its many molecular motors are major players in a variety of cellular functions. The interconnected networks of cytoskeletal filaments act as tracks directing molecular motor transport and provide structural support and organization to cells. One example of … Read More

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