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Transcription factors and chromatin co-condensate and generate forces that alter genomic structure and function

Researchers led by Yael David and Shixin Liu have published a Nature Communications study describing for the first time the mechanisms underlying the co-condensation between transcription factors and DNA. By performing dynamic single-molecule experiments using LUMICKS’ C-Trap® technology, they were able to prove the physiological importance of phase-separated sub-compartments (co-condensates)…
Chenlu Yu
7 December 2022
Blog posts

New C-Trap® installation at Radboud University to offer insights into chromatin organization

We are thrilled to announce the installation of a C-Trap® at the RIMLS-Science institute, Radboud University, The Netherlands, in the lab of Dr. Jorine Eeftens. The installed C-Trap combines dual-trap optical tweezers with super-resolution confocal microscopy, which will allow the team to perform and visualize single-molecule experiments with unprecedented detail to…
Chenlu Yu
14 April 2022
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