DNA–binding proteins

Part of: Applications

Today’s scientific trends are racing towards smaller scales and experimentation that provides both structural and mechanistic insights. To decipher biomolecular mechanisms you need methods capable of detecting the interactions between proteins and nucleic acids as they happen and at the molecular level.

We offer solutions that enable you to measure, manipulate, and visualize DNA-protein interaction in real-time and at the single-molecule level, with both high throughput and resolution. Uncover the structure, function, and dynamic interplay between proteins and nucleic acids.

DNA editing

On/Off-target binding
DNA-binding protein localization
Real-time binding visualization
Genomic location of binding events

DNA/RNA structure

Conformational transitions
Structure, function & dynamics
DNA-DNA interactions
Drug-DNA interactions

DNA organization

Histones and nucleosomes
Conformational changes
Protein effect, target site, activity, binding kinetics
Drug-molecule interactions

DNA repair

Protein effect, target site, activity, binding kinetics
Drug-molecule interactions

DNA transcription

Transcription control
Motor Stepping & activity
Protein effect, target site, activity, binding kinetics
Drug-molecule interactions

DNA replication

Transcription control
Motor Stepping & activity
Protein effect, target site, activity, binding kinetics
Drug-molecule interactions

RNA translation

Translation control
Ribosome stepping mechanism
Protein effect, target site, activity, binding kinetics
Drug-molecule interactions

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Dynamic single-molecule analysis

Cell avidity analysis

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