Top banner image was licensed by Sergey Novikov / Shutterstock.comUncategorised

C-Trap® installed at Technical University of Munich

We are happy to announce the recent installation of the C-Trap® at the Technical University of Munich, Germany, in the lab of Prof. Matthias Rief. The installed C-Trap combines optical tweezers with 2-color fluorescence microscopy and will be used by students and postdocs in the Rief lab. Among other areas,…
j.yeh
11 February 2020
Uncategorised

Dynamic Single-Molecule Workshops in North and South of China

Last week we organized two dynamic single-molecule workshops in the North and South of China – one at Tsinghua University in Beijing, and another at  Sun Yat-sen University (SYSU). Both workshops included in-depth lectures exploring different state-of-the-art single-molecule applications and hands-on demonstrations of the C-Trap® Optical Tweezers – Fluorescence & Label-free Microscopy technologies. With…
j.yeh
18 December 2019
Uncategorised

C-Trap® installed at Tel Aviv University

  We are happy to announce the recent installation of the C-Trap™ at Tel Aviv University, Israel, in the lab of Dr. Raya Sorkin. The C-Trap combines optical tweezers with confocal microscopy and is now available to students and postdocs in Dr. Sorkin’s lab, as well as several collaborators on…
j.yeh
11 December 2019
Uncategorised

Single-molecule study assesses how cohesin complexes bridge DNA molecules using C-Trap® correlated optical tweezers with fluorescence microscopy

In a new study published in the journal Science Advances, Gutierreu-Flux™Escribano et al. studied the role of cohesin complexes in DNA tethering to gain a better understanding of sister chromatid cohesion. Using the C-Trap correlated optical tweezers with fluorescence microscopy, they observed in real-time intermolecular (DNA–DNA) and intramolecular cohesin-derived DNA bridge…
j.yeh
5 December 2019
Top banner image was licensed by The University of Vermont / Flickr.Uncategorised

C-Trap® installed at University of Vermont

We are happy to announce the recent installation of the C-Trap® at the University of Vermont Larner College of Medicine. Several labs will use the correlated optical tweezers – fluorescence microscopy instrument to investigate the dynamics of molecular machines that interact with their tracks to generate force and motion. These processes are…
j.yeh
22 October 2019
C-Trap Albert Einstein College of MedicineUncategorised

C-Trap® installed at Albert Einstein College of Medicine

We are happy to announce the installation of the C-Trap™ at the Albert Einstein College of Medicine in New York in the lab of Prof. Dr. Arne Gennerich. The instrument combines optical tweezers with 3-color total internal reflection fluorescence (TIRF; a technology that reduces fluorescence background noise in surface-based assays)…
j.yeh
1 October 2019
New C-Trap® Installed at the University at BuffaloUncategorised

Study establishes molecular forces responsible for condensation of ribonucleoprotein-RNA complexes

Researchers investigated the molecular driving forces underlying the condensation and decondensation of ribonucleoproteins using the C-Trap™. Specifically, they showed that sequence-dependent features of the RNA and ribonucleoprotein molecules partially dictate phase transitions. These findings can help scientists further understand the properties underlying eukaryotic liquid-liquid phase separation, or formation of membrane-less…
j.yeh
5 September 2019
Uncategorised

New study evaluates the dynamics behind viral assembly at the single-molecule level using both C-Trap™ and AFS®

Researchers used the C-Trap™ optical tweezers – fluorescence microscopy system and acoustic force spectroscopy (AFS) to study the processes underlying viral assembly. The study evaluated the capsid formation and DNA condensation of virus-like particles (VLPs) at the single-molecule level and in real time. The results serve to expand our understanding…
j.yeh
22 August 2019

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