News

Evaluation of protein droplet viscoelasticity with the C-Trap® reveals new material properties

A recent publication in Science describes a new glass-like structural behavior that protein droplets can adopt, regulating their biochemical behavior as they age. Specifically, through rheological measurements using the C-Trap® optical tweezers, the researchers discovered material properties that may help cells respond to a dynamic molecular environment. The findings offer essential insights into the…
Kassandra Barbetsea
16 February 2021
News

Researchers investigate the effects of biomolecular droplet structure on fusion times using the C-Trap®

In a recent publication, researchers at the University of Illinois at Chicago used the C-Trap® to study the relationship between structural properties of biomolecular condensates and their fusion times. They found that fusion times, an indicator of condensate density, varies depending on their structural organization. The findings highlight how physical…
Kassandra Barbetsea
27 August 2020
New C-Trap® Installed at the University at BuffaloUncategorised

Study establishes molecular forces responsible for condensation of ribonucleoprotein-RNA complexes

Researchers investigated the molecular driving forces underlying the condensation and decondensation of ribonucleoproteins using the C-Trap™. Specifically, they showed that sequence-dependent features of the RNA and ribonucleoprotein molecules partially dictate phase transitions. These findings can help scientists further understand the properties underlying eukaryotic liquid-liquid phase separation, or formation of membrane-less…
Kassandra Barbetsea
5 September 2019

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