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news

C-Trap® installed at Imperial College London, UKnews

LUMICKS DSM technologies installed in South East UK

We are happy to share our news about the most recent C-Trap® and m-Trap® installations in the UK! We’ll start with the recently installed C-Trap® system at the MRC-London Institute of Medical Sciences, Imperial College London that is used by the cell biologists and biochemists at the group of Prof.…
Ron Eliyahoo
4 May 2021
news

Highly reproducible single-molecule analysis of transient structures of native proteins using m-Trap® dual optical tweezers combined with Raman spectroscopy

A recent publication by Dai et al. in Nature Communications presents an optical tweezers-coupled Raman spectroscopy platform providing tuneable and reproducible surface-enhanced Raman spectroscopy (SERS) measurements. By combining a Raman microscope with the dual-trap optical tweezers and microfluidic flow chamber of the m-Trap®, the scientists were able to characterize three…
Nelli Bossert
8 April 2021
C-Trap® installed at University of Groningen, NLnews

New C-Trap® installation at the University of Groningen opens avenues for investigating the conformational cycle of chaperone proteins

We are thrilled to announce the installation of a C-Trap® at the University of Groningen, Netherlands, in the lab of Dr. Katarzyna (Kasia) Tych. The installed C-Trap® combines optical tweezers with 3-color fluorescence microscopy, which the team will use to investigate protein stabilities, molecular chaperoning, and conformational regulation. They plan…
Ron Eliyahoo
23 March 2021
ROS activation in macrophages optical tweezers fluorescence microscopynews

Early activation of single macrophages captured by the C-Trap®

In a recent article published in Small Methods, researchers reveal a method that uniquely captures the early phase of oxidative stress response in macrophages. Employing the powerful combination of optical tweezers, confocal fluorescent microscopy, and microfluidics of the C-Trap®, they measured the real-time intracellular response of individual macrophages to a…
Nelli Bossert
11 March 2021
Top banner images were licensed by Jose Luis Stephens (Santiago de Chile) / Sean Pavone (Salt Lake City) / Boris Stroujko (Wurzburg) / f11photo (Tokyo) / Shutterstock.comnews

LUMICKS technologies installed all around the world

As turbulent 2020 was, we are happy to have managed to install various LUMICKS instruments all around the world. Our dynamic single-molecule instruments enable researchers to analyze complex dynamic details related to the behavior and interaction of single molecules. One of these installations is the newly installed C-Trap® system at the…
Doenja Jansen
23 February 2021
news

The softening effect of vimentin filament phosphorylation measured with the C-Trap®

A recent study published in the journal Nanoscale shows how post-translational phosphorylation and proteins binding phosphorylated sites regulate the stiffness of vimentin filaments. The researchers combined several analytical approaches and instruments, including the C-Trap® optical tweezers, to define the role of these modifications and interactions on the mechanical properties of vimentin. Apart from contributing…
Santiago Gisler
16 February 2021