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Blog posts

From Handshakes to Hugs: Embracing the Dynamics of Immunological Synapse Strength and Avidity 

What is an immune synapse?  An immunological (or immune) synapse is the interface between a cancer and an immune cell , which is formed in a highly stable, organized manner. The immunological synapse is composed of all intercellular interactions taking place at the interface between the interacting pair, including TCR clustering, co-receptor binding, cell-cell adhesion…
Adrià Ferragut
17 January 2024
Blog posts

Cell mechanics with the C-Trap – cellular tension propagation revisited

Surprising insights into the roles of membranes and the actin cytoskeleton in cellular tension propagation – congratulations to all authors for successfully implementing a new and elegant assay with the C-Trap!   There was a long-standing dispute in the scientific community about whether the actin cortex facilitates or impedes tension propagation…
Chenlu Yu
28 November 2023
Blog posts

Putting our unused lab equipment to better use

We are excited to announce that LUMICKS is donating laboratory equipment for a summer course in Yobe, Nigeria, organized by the Biomedical Science Research and Training Centre (BioRTC) and Trend In Africa. We added various tools from our LUMICKS C-Trap® head quarters to the donation. Nigeria has a huge shortage…
Laura Triana
26 May 2023
Blog posts

100th study using the C-Trap® provides crucial insights into how the Smc5/6 complex stabilizes certain DNA structures  

A recent study published in Nature Communications led by Shixin Liu from The Rockefeller University, New York, demonstrates how the C-Trap® can be used to directly visualize and observe molecular mechanisms in action, leading to better and faster insights into critical molecular processes. This study marks an important milestone for LUMICKS,…
Chenlu Yu
28 March 2023
Blog posts

C-Trap® experiments shed light on the mechanisms that govern Structural Maintenance of Chromosome (SMC) Complexes  

In two recent scientific publications, Johannes Stigler and his team from the Gene Center of the Ludwig-Maximilians-University Munich, Germany, set out to mechanistically describe the action of the Structural Maintenance of Chromosome (SMC) Complexes using LUMICKS’ C-Trap® technology. By performing dynamic single-molecule experiments coupled with real-time visualization, they were able…
Chenlu Yu
9 March 2023
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