Uncategorised

New study evaluates the dynamics behind viral assembly at the single-molecule level using both C-Trap™ and AFS®

Researchers used the C-Trap™ optical tweezers – fluorescence microscopy system and acoustic force spectroscopy (AFS) to study the processes underlying viral assembly. The study evaluated the capsid formation and DNA condensation of virus-like particles (VLPs) at the single-molecule level and in real time. The results serve to expand our understanding…
j.yeh
22 August 2019
DSM Summer School, Beijing 2019Uncategorised

First Dynamic Single-Molecule Summer School in China!

Yet another premiere! LUMICKS organized the very first Dynamic Single-Molecule Summer School at Tsinghua University in Beijing. During the three-day event, nineteen participants received in-depth training in both the theory and practice of dynamic single-molecule (DSM) techniques. Our application scientists dedicated the mornings for lectures on various topics involved in DSM…
j.yeh
14 August 2019
C-Trap® & AFS™ installed at Tianjin UniversityUncategorised

C-Trap™ & AFS™ installed at Tianjin University

LUMICKS is proud that Tianjin University, China, is now equipped with both a C-Trap® Optical Tweezers-Fluorescence Microscopy and AFS™ Parallel Single-Molecule Force Spectroscopy. The systems are installed in the State Key Laboratory of Precision Measurement Technology and Instruments. Both systems will contribute to the research on processes involved in protein unfolding pathways. First, the…
j.yeh
19 July 2019
Uncategorised

Researchers used u-Flux™ and optical tweezers to measure RecBCD activity

In a study performed at the Technion – Israel Institute of Technology, researchers used our  u-Flux™ laminar flow microfluidics system combined with optical tweezers to investigate the activity of the Escherichia coli enzyme RecBCD and its subunits. The paper titled “Synergy between RecBCD subunit is essential for efficient DNA unwinding” appeared…
j.yeh
11 July 2019
Blog posts

Second C-Trap installed at TU Delft

Another exciting installation in the Netherlands! This time we installed the second C-Trap® Optical Tweezers-Fluorescence Microscopy in the Department of Bionanoscience at the TU Delft, a top tier Dutch university. The system was installed in the lab of Prof. Nynke Dekker. The Nynke Dekker Lab studies the cellular process involved…
j.yeh
3 July 2019
Dynamic Single-Molecule Workshop at HQ AmsterdamUncategorised

Dynamic Single-Molecule Workshop at HQ Amsterdam

Last week, LUMICKS organized a successful Dynamic Single-Molecule Workshop at our headquarters in Amsterdam. Throughout the workshop, the participants explored different state-of-the-art single-molecule applications and attended various technology presentations and discussion. Also, Prof. Sander Tans (AMOLF) presented his studies with optical tweezers, analyzing a possible direct or indirect role of chaperone proteins in the folding…
j.yeh
26 June 2019
C-Trap® SR installed at the National Institutes of Health (NIH)Uncategorised

C-Trap® SR installed at the National Institutes of Health (NIH)

A new C-Trap® SR was installed at the National Institutes of Health, Maryland, USA, in the labs of Prof. Antonina Roll-Mecak and Prof. Keir Neuman. The LUMICKS optical tweezers-STED nanoscopy system allows the user to visualize molecular interactions with super-resolution microscopy. The highly interdisciplinary group of Prof. Roll-Mecak works on unraveling the chemical and genetic complexity of the microtubule cytoskeleton, or "the tubulin code". The…
Jerom Langeveld
14 May 2019
Single-Molecule Workshop at ShanghaiTechUncategorised

Dynamic Single-Molecule Workshop at the ShanghaiTech University

The first dynamic single-molecule workshop of the year just came to an end! Last week, 16 participants got to experience the C-Trap® Optical Tweezers – Fluorescence Microscope to investigate DNA mechanics and do experiments using their own samples. Additionally, the workshop included lectures from Prof. Bo Sun, during which he discussed his…
j.yeh
26 April 2019

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