DNA replication Archives

Blog posts

The C-Trap uncovers new insights into the mechanisms for ATP-dependent chromatin remodeling

PICH (Plk1-interacting checkpoint helicase) belongs to the SNF2 family of ATP-dependent chromatin remodelers. However, what makes PICH unique is that it lacks a nucleotide-binding domain despite having a great affinity for bare DNA. Because of this molecular structure, it has been hypothesized that the binding of PICH to chromatinized bridges…

Chenlu Yu13 June 2023

Blog posts

100th study using the C-Trap^® provides crucial insights into how the Smc5/6 complex stabilizes certain DNA structures

A recent study published in Nature Communications led by Shixin Liu from The Rockefeller University, New York, demonstrates how the C-Trap® can be used to directly visualize and observe molecular mechanisms in action, leading to better and faster insights into critical molecular processes. This study marks an important milestone for LUMICKS,…

Chenlu Yu28 March 2023

Blog posts

Three C-Trap^® systems installed in the US East Coast

We are excited to share that three more institutes on the US East Coast are now equipped with a C-Trap® Optical Tweezers – Fluorescence Microscope! The three new instruments are now housed at a new core facility at MSKCC, at the NanoSystems Laboratory at the OSU, and at the UPMC-Hillman Cancer…

j.yeh17 May 2021

C-Trap® installed at Imperial College London, UK

Blog posts

LUMICKS DSM technologies installed in South East UK

We are happy to share our news about the most recent C-Trap® and m-Trap® installations in the UK! We’ll start with the recently installed C-Trap system at the MRC-London Institute of Medical Sciences, Imperial College London that is used by the cell biologists and biochemists at the group of Prof. Luis…

Adrià Ferragut4 May 2021

Blog posts

New study resolves helicase dynamics and interactions during DNA replication using C-Trap^®

Researchers from Rockefeller University used a C-Trap® optical tweezers – fluorescence microscopy system to observe the behavior of the main component of the replisome – the eukaryotic CMG helicase – during DNA replication. The study offers exciting new insights into the interactions, processes, and structural plasticity associated with CMG during…

j.yeh26 July 2019

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DNA replication Archives - LUMICKS

The C-Trap uncovers new insights into the mechanisms for ATP-dependent chromatin remodeling

100th study using the C-Trap^® provides crucial insights into how the Smc5/6 complex stabilizes certain DNA structures

Three C-Trap^® systems installed in the US East Coast

LUMICKS DSM technologies installed in South East UK

New study resolves helicase dynamics and interactions during DNA replication using C-Trap^®

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DNA replication Archives - LUMICKS

The C-Trap uncovers new insights into the mechanisms for ATP-dependent chromatin remodeling

100th study using the C-Trap® provides crucial insights into how the Smc5/6 complex stabilizes certain DNA structures

Three C-Trap® systems installed in the US East Coast

LUMICKS DSM technologies installed in South East UK

New study resolves helicase dynamics and interactions during DNA replication using C-Trap®

Recent Posts

Yearly Archive

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About LUMICKS

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100th study using the C-Trap^® provides crucial insights into how the Smc5/6 complex stabilizes certain DNA structures

Three C-Trap^® systems installed in the US East Coast

New study resolves helicase dynamics and interactions during DNA replication using C-Trap^®