Blog posts

Vesicle-like RNA–protein condensates characterized by the C-Trap®

We were happy to find yet another publication from the lab of Dr. Priya Banerjee with results from C-Trap® analyses! This time his lab examined the formation and features of vesicle-like RNA–protein structures, which differ from the more known uniform droplets. Apart from offering new insights to an emerging field,…
j.yeh
9 July 2020
Blog posts

Exploring mitochondrial translation processes with the C-Trap®

This month, we find the C-Trap®  featured in Nature Communications in an article published by the lab of Dr. Joanna Rorbach in which they describe mitochondrial translation initiation. The study provides insight into a relatively unexplored, yet exciting field that investigates the properties of mitochondrial ribosomes (mitoribosomes) during translation. Understanding…
j.yeh
25 June 2020
Blog posts

Recent review highlights the impact of force spectroscopy and the C-Trap®

We were happy to read last week that LUMICKS was recognized for our efforts in the field of dynamic single-molecule research! A recent review in ACS Publications examined the current advances in single-molecule research, highlighting the impact of force spectroscopy techniques to biology, including optical tweezers, magnetic tweezers, and atomic…
j.yeh
21 May 2020
Uncategorised

Controlled ligand gradient through C-Trap® facilitates DSM measurements

A publication in the journal Micromachines describes how researchers managed to control the concentrations of DNA-binding dyes in single-molecule optical tweezers experiments on DNA. They established a controlled concentration gradient with the multi-channel laminar microfluidics system integrated with their C-Trap® correlated optical tweezers and confocal microscopy. The study demonstrates a…
j.yeh
19 March 2020
Blog posts

Impressions from LUMICKS’ Training Session for new users

As part of our commitment to support scientists through all the stages towards their first publication using our instruments, we often organize dedicated training sessions. In the case of the lab of Prof. Shi at Tsinghua University, this was in the form of a 5-day advanced training, providing in-depth knowledge…
Ron Eliyahoo
16 March 2020
Uncategorised

Study shows detailed properties of Ca2+ sensors during membrane fusion

A recent study in the Biophysical Journal shows how a Dutch research group measured and visualized dynamic interactions between membranes in the presence of Ca2+ sensors and synaptic inducers Syt1 and Doc2b. With the combined optical tweezers and confocal fluorescence microscopy configuration of the C-Trap®, the team revealed Ca2+ sensor-dependent…
j.yeh
12 March 2020
Uncategorised

A new DNA–protein coupling procedure improves stability for DSM analyses

A recent study in Communications Chemistry shows how a research lab at AMOLF in the Netherlands optimized DNA–protein coupling to study dynamic processes requiring high forces and long-term assessments. Using their C-Trap® Optical Tweezers – Fluorescence Microscopy system, the team showed the superiority of a ligation-based strategy to create long…
j.yeh
5 March 2020
Uncategorised

Study shows how chaperone enzyme ClpB processively translocates polypeptide loops using C-Trap® correlated optical tweezers and confocal microscopy

A new study published in Nature reports how researchers verified the intricate process of disaggregating entangled proteins by analyzing chaperone enzyme ClpB at a single-molecule level. The C-Trap® correlated optical tweezers and confocal microscopy enabled them to analyze how the member of the Hsp100 chaperone family translocates looped polypeptide substrates…
j.yeh
13 February 2020

Join our newsletter

Join our newsletter

Get exclusive news on the latest publications, product developments, events and breakthrough science.

By agreeing to receive marketing communications, you subscribe to our newsletter. You can change your mind at any time by clicking the unsubscribe link in any marketing email you receive from us. By submitting the form you agree to LUMICKS' privacy policy.

Download our webinar recording:

 

Download our Cell Therapy (CAR-T, TCR, NK) applications deck