We walk you through a case study, where our researchers examined the conformational properties of adenylate kinase (AdK) upon exposure to kinase inhibitor di(adenosine-5′) pentaphosphate (AP5A). We explain how the C-Trap can collect real-time data of single proteins and capture discrete conformational changes that reveal their functional properties. You will learn:
How we tether a single protein to optically trapped beads.
How we measure conformational changes of AdK upon exposure to small-molecule inhibitor AP5A.
The workflow and features that make these types of experiments fast and straightforward, regardless of your previous experience level.
Download a copy of the application note here on the right to discover how you can perform real-time protein assessments with nanometer precision to extract the full conformation dynamics.
Feel free to contact us if you want more information about the C-Trap® or our other instruments for single-molecule or single-cell research.
Analytical cookies are used to understand how visitors interact with the website. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc.
The _ga cookie, installed by Google Analytics, calculates visitor, session and campaign data and also keeps track of site usage for the site's analytics report. The cookie stores information anonymously and assigns a randomly generated number to recognize unique visitors.
Set by Google to distinguish users.
Provided by Google Tag Manager to experiment advertisement efficiency of websites using their services.
Installed by Google Analytics, _gid cookie stores information on how visitors use a website, while also creating an analytics report of the website's performance. Some of the data that are collected include the number of visitors, their source, and the pages they visit anonymously.
Clarity is a user behavior analytics tool that helps you understand how users are interacting with our website through session replays and heatmaps.
Google Analytics Universal
A variation of the _gat cookie set by Google Analytics and Google Tag Manager to allow website owners to track visitor behaviour and measure site performance. The pattern element in the name contains the unique identity number of the account or website it relates to.
The pardot cookie is set while the visitor is logged in as a Pardot user. The cookie indicates an active session and is not used for tracking.