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C-Trap Archives - Page 5 of 12 - LUMICKS

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C-Trap® installed at Tel Aviv University

  We are happy to announce the recent installation of the C-Trap™ at Tel Aviv University, Israel, in the lab of Dr. Raya Sorkin. The C-Trap combines optical tweezers with confocal microscopy and is now available to students and postdocs in Dr. Sorkin’s lab, as well as several collaborators on…
Santiago Gisler
11 December 2019
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Single-molecule study assesses how cohesin complexes bridge DNA molecules using C-Trap® correlated optical tweezers with fluorescence microscopy

In a new study published in the journal Science Advances, Gutierrez-Escribano et al. studied the role of cohesin complexes in DNA tethering to gain a better understanding of sister chromatid cohesion. Using the C-Trap correlated optical tweezers with fluorescence microscopy, they observed in real-time intermolecular (DNA–DNA) and intramolecular cohesin-derived DNA bridge…
Santiago Gisler
5 December 2019
Top banner image was licensed by The University of Vermont / Flickr.Uncategorised

C-Trap® installed at University of Vermont

We are happy to announce the recent installation of the C-Trap™ at the University of Vermont Larner College of Medicine. Several labs will use the correlated optical tweezers – fluorescence microscopy instrument to investigate the dynamics of molecular machines that interact with their tracks to generate force and motion. These processes are…
Santiago Gisler
22 October 2019
C-Trap Albert Einstein College of MedicineUncategorised

C-Trap® installed at Albert Einstein College of Medicine

We are happy to announce the installation of the C-Trap™ at the Albert Einstein College of Medicine in New York in the lab of Prof. Dr. Arne Gennerich. The instrument combines optical tweezers with 3-color total internal reflection fluorescence (TIRF; a technology that reduces fluorescence background noise in surface-based assays)…
Santiago Gisler
1 October 2019
New C-Trap™ Installed at the University at BuffaloUncategorised

Study establishes molecular forces responsible for condensation of ribonucleoprotein-RNA complexes

Researchers investigated the molecular driving forces underlying the condensation and decondensation of ribonucleoproteins using the C-Trap™. Specifically, they showed that sequence-dependent features of the RNA and ribonucleoprotein molecules partially dictate phase transitions. These findings can help scientists further understand the properties underlying eukaryotic liquid-liquid phase separation, or formation of membrane-less…
Santiago Gisler
5 September 2019
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New study evaluates the dynamics behind viral assembly at the single-molecule level using both C-Trap™ and AFS®

Researchers used the C-Trap™ optical tweezers – fluorescence microscopy system and acoustic force spectroscopy (AFS) to study the processes underlying viral assembly. The study evaluated the capsid formation and DNA condensation of virus-like particles (VLPs) at the single-molecule level and in real time. The results serve to expand our understanding…
Santiago Gisler
22 August 2019
DSM Summer School, Beijing 2019Uncategorised

First Dynamic Single-Molecule Summer School in China!

Yet another premiere! LUMICKS organized the very first Dynamic Single-Molecule Summer School at Tsinghua University in Beijing. During the three-day event, nineteen participants received in-depth training in both the theory and practice of dynamic single-molecule (DSM) techniques. Our application scientists dedicated the mornings for lectures on various topics involved in DSM…
Doenja Jansen
14 August 2019

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