Application note describing the use of C-Trap to study cell mechanics and functions available for downloading

We are happy to announce that our latest application note “Manipulating and Studying Cellular Mechanics and Functions in Real Time” is available to download on our website.

In this application note, you can read how we, together with three different research groups, used the C-Trap™ optical tweezers – fluorescence & label-free microscopy system to study diverse features associated with cellular mechanics and functions in real time. We present three research-specific approaches using the C-Trap to analyze cell properties in diverse contexts:

  • How mechanical stimuli or stresses affect cell receptor responses – together with the Javitch Lab at Columbia University in New York,
  • Filopodia formation and functions – together with the Titus Lab at the University of Minnesota in Minneapolis,
  • Cellular droplet fusion and small components in a multicellular organism – together with the Starr Lab at the University of California in Davis.

We thank all our collaborators for the excellent teamwork and wish you continued success in your future research.

Do you want to read the application note and learn more about the experiments? You can download the document here.

Feel free to contact us if you want more information about the C-Trap or our other instruments for single-molecule and single-cell research.

Want to learn more about this application and our solutions?

Cellular Signaling and Function

Receptor accumulation
Filopodia formation and dynamics
Localization, fusion, and aggregation of cell components

Optical Tweezers and Fluorescence Microscopy

Technology

The combination of optical tweezers and fluorescence microscopy allows for simultaneous manipulation and visualization of molecular interactions in real-time.

Solutions

C-Trap

Optical Tweezers and Fluorescence Microscopy

m-Trap

Optical Tweezers

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