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C-Trap

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Electrostatic effects on vimentin stiffness demonstrated with the C-Trap®

A recently published study from the lab of Prof. Sarah Köster at the University of Göttingen investigated how electrostatic conditions influence the mechanical properties of intermediate filament vimentin, such as structural stability. The researchers assessed these features by stretching the protein in different buffer conditions, using the C-Trap® with correlated optical…
j.yeh
6 August 2020
Blog posts

Vesicle-like RNA–protein condensates characterized by the C-Trap®

We were happy to find yet another publication from the lab of Dr. Priya Banerjee with results from C-Trap® analyses! This time his lab examined the formation and features of vesicle-like RNA–protein structures, which differ from the more known uniform droplets. Apart from offering new insights to an emerging field,…
j.yeh
9 July 2020
Blog posts

Exploring mitochondrial translation processes with the C-Trap®

This month, we find the C-Trap®  featured in Nature Communications in an article published by the lab of Dr. Joanna Rorbach in which they describe mitochondrial translation initiation. The study provides insight into a relatively unexplored, yet exciting field that investigates the properties of mitochondrial ribosomes (mitoribosomes) during translation. Understanding…
j.yeh
25 June 2020
Blog posts

Recent review highlights the impact of force spectroscopy and the C-Trap®

We were happy to read last week that LUMICKS was recognized for our efforts in the field of dynamic single-molecule research! A recent review in ACS Publications examined the current advances in single-molecule research, highlighting the impact of force spectroscopy techniques to biology, including optical tweezers, magnetic tweezers, and atomic…
j.yeh
21 May 2020
Blog posts

Controlled ligand gradient through C-Trap® facilitates DSM measurements

A publication in the journal Micromachines describes how researchers managed to control the concentrations of DNA-binding dyes in single-molecule optical tweezers experiments on DNA. They established a controlled concentration gradient with the multi-channel laminar microfluidics system integrated with their C-Trap® correlated optical tweezers and confocal microscopy. The study demonstrates a…
j.yeh
19 March 2020
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