Impressions from LUMICKS’ Training Session for new users

As part of our commitment to support scientists through all the stages towards their first publication using our instruments, we often organize dedicated training sessions. In the case of the lab of Prof. Shi at Tsinghua University, this was in the form of a 5-day advanced training, providing in-depth knowledge in both the theory and practice of Dynamic Single-Molecule (DSM) techniques.

“With the help of LUMICKS, my student started using this equipment after about 30 minutes of training [and] was quickly able to generate lots of data from it. I feel like this is going to be a very exciting tool in my lab that can help us to answer many important questions we have.” Prof. Shi, Tsinghua University, Beijing, China

Prof. Shi uses a combination of structural and functional approaches to resolve structures of RNA molecules and identify their functions. Having had minimal prior experience with single-molecule tools such as optical tweezers, this training helped them investigate the free energy related to RNA conformational changes in no time.

Are you interested in adopting new tools to investigate biomolecular processes at the single-molecule level and in real-time? Have a look at our products and services.

Want to learn more about this application and our solutions?

DNA/RNA Structural Mechanics

Conformational transitions
Structure, function & dynamics
DNA-DNA interactions
Drug-DNA interactions

RNA Translation

Translation control
Ribosome stepping mechanism
Protein effect, target site, activity, binding kinetics
Drug-molecule interactions

Optical Tweezers and Fluorescence Microscopy

Technology

The combination of optical tweezers and fluorescence microscopy allows for simultaneous manipulation and visualization of molecular interactions in real-time.

Solutions

C-Trap

Optical Tweezers and Fluorescence Microscopy

m-Trap

Optical Tweezers

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