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C-Trap

Single-Molecule Workshop at ShanghaiTechBlog posts

Dynamic Single-Molecule Workshop at the ShanghaiTech University

The first dynamic single-molecule workshop of the year just came to an end! Last week, 16 participants got to experience the C-Trap® Optical Tweezers – Fluorescence Microscope to investigate DNA mechanics and do experiments using their own samples. Additionally, the workshop included lectures from Prof. Bo Sun, during which he discussed his…
j.yeh
26 April 2019
C-Trap® SR installed at Northeastern UniversityBlog posts

C-Trap™ SR installed at Northeastern University

We are happy to have installed a C-Trap® SR, our optical tweezers-STED nanoscope, in shared lab space for an interdisciplinary group led by Prof. Mark Williams at Northeastern University, in Massachusetts, USA. The lab of Prof. Williams is highly regarded as one of the leaders of single-molecule analysis, making us even more proud of this installation. The lab focuses…
j.yeh
16 April 2019
C-Trap installation at Sun Yat-sen University, ChinaBlog posts

C-Trap™ installed at Sun Yat-sen University, China

School of Physics at the Sun Yat-sen University, China, is now equipped with a C-Trap™ Optical Tweezers-Fluorescence Microscope. This advanced instrument is believed to be able to boost up a variety of exciting researches in SYSU, such as DNA/RNA mechanics and protein-DNA or -RNA interactions during DNA replication, transcription, and repair that Prof.…
j.yeh
8 April 2019
C-Trap installation at B CUBE TU DresdenBlog posts

Second C-Trap™ installed in Dresden, Germany

The city of Dresden, Germany, is now the home of two C-Trap® systems! The latest installation took place at the Center for Molecular and Cellular Bioengineering at TU Dresden, where the instrument became part of the Joint Technology Platform. Being operated in the "Molecular Imaging and Manipulation" facility, the system will be available to multiple…
j.yeh
26 March 2019
Blog posts

New insights into Cas9 off-target activity

The paper “DNA stretching induces Cas9 off-target binding and cleavage” was just published in Nature Structural and Molecular Biology. Congratulations to all the authors! In this paper, scientists at the MRC London Institute of Medical Sciences and AstraZeneca studied how CRISPR-Cas9 differentiates between on-targets and off-targets. They used the C-Trap®…
j.yeh
8 March 2019
C-Trap m-Trap 2019 Brochure CoversBlog posts

Step into the unresolved with the Surface Assay Toolkit

During BPS19, we introduced the Surface Assay Toolkit! A unique assortment of new features that enable scientists to investigate the cytoskeleton from a whole new dynamic perspective. The Surface Assay Toolkit brings together the C-Trap™ and m-Trap™ optical tweezers with:  Label-free surface imaging using IRM;  Rapid fluorescent imaging in solution using Widefield;  Fluorescence surface imaging using TIRF;  High throughput experimental workflow at the surface. Download the 2019…
j.yeh
7 March 2019
C-Trap Installation at UC MercedBlog posts

C-Trap™ installed at UC Merced

A C-Trap™, optical tweezers coupled with fluorescence microscopy, has been successfully installed at the University of California, Merced. The system is shared by the research groups of Prof. Eva de Alba and Prof. Victor Muñoz. Their labs focus on the study of proteins, which are involved in almost all cellular processes. This makes the…
Jerom Langeveld
18 February 2019
Blog posts

C-Trap installed at TU Delft

We are thrilled about the recent C-Trap® installation in the Department of Bionanoscience at the TU Delft, one of the leading universities in The Netherlands! The groups of Prof. Nynke Dekker and Prof. Marileen Dogterom will use the C-Trap to study the dynamic aspects of DNA replication and cytoskeleton-based processes,…
Jerom Langeveld
13 December 2018
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