j.yeh

Blog posts

New study highlights interconvertible RecA–ssDNA states with the help of u-Flux™ microfluidics

A recent publication in FEBS Letters describes how the presence of ADP and ATP affects the structural transitions that single-stranded DNA (ssDNA) undergoes upon RecA-filament assembly. The researchers used the u-Flux™ Laminar Flow Microfluidics combined with optical tweezers to demonstrate that the bacterial homologous recombination-enzyme exists in two interconvertible states.…

j.yeh29 October 2020

Blog posts

Force-dependent actin filament-binding by α-catenin recorded with the C-Trap^®

A recent publication in the journal eLife describes a multidisciplinary study evaluating how the mechanical properties of actin filaments regulate the binding of associated proteins. Specifically, the researchers used the C-Trap® to demonstrate how applied forces on actin filaments enhance binding of cell–cell adhesion protein α-catenin, but not its homolog…

j.yeh15 October 2020

Blog posts

C-Trap^® installed at the National Center for Biotechnology in Madrid

We are happy to announce the installation of a C-Trap® Optical Tweezers – Fluorescence and Label-free Microscopy system at the National Center for Biotechnology (CNB), Madrid, managed by the lab of Dr. Fernando Moreno-Herrero. The team will use the C-Trap configured with dual traps and correlated three-color confocal to examine…

j.yeh12 October 2020

Press releases

Introduction of LUMICKS consumables and script-sharing platform to facilitate faster, easier, and more reproducible Dynamic Single-Molecule analysis

In a move to broadly unlock Dynamic Single-Molecule (DSM) analysis, LUMICKS simultaneously launched two major initiatives: a new business line for reagents, biochemistry kits, and services, as well as its Harbor platform for sharing of DSM scripts. These new resources dramatically simplify the experimental workflow and make DSM analysis accessible…

j.yeh2 October 2020

Blog posts

LUMICKS featured in LinkedIn Top Start-ups 2020

LUMICKS reached the 6th position in the list LinkedIn Top Start-ups 2020 in the Netherlands. We're extremely proud to be among the most resilient companies during these changing times. The LinkedIn editors define start-ups as privately held companies, that are no more than seven years old, employ over 50 people, and…

j.yeh22 September 2020

Blog posts

New application note shows how to study transient conformational changes of kinases using the C-Trap^®

We are excited to announce that our latest application note, Real-time detection of kinase conformational changes in the presence of a small-molecule inhibitor, is available to download. The application note is perfect for protein research, as it showcases how you can use the C-Trap® Optical Tweezers – Fluorescence & Label-free…

j.yeh17 September 2020

Blog posts

Researchers use the m-Trap^® and C-Trap^® to discover CRISPR-Cas9 properties that can help improve in vivo efficiency

A recent publication from the research lab of Dr. Bo Sun presents new findings in the field of gene editing that may help improve in vivo delivery of CRISPR-Cas9 complexes. The team investigated the DNA-binding properties of Staphylococcus aureus Cas9 (SaCas9), a smaller orthologue to the commonly used Streptococcus pyogenes…

j.yeh10 September 2020

Press releases

LUMICKS opens new branch office in Beijing to serve the Asian market

LUMICKS is proud to announce the opening of its branch office in Beijing, China. As LUMICKS continues to expand within the rapidly developing life sciences and immuno-oncology market in the Asia Pacific Region (APR), the new office will allow to better serve the market opportunity, support local customers, and collaborate…

j.yeh28 August 2020

Blog posts

Researchers investigate the effects of biomolecular droplet structure on fusion times using the C-Trap^®

In a recent publication, researchers at the University of Illinois at Chicago used the C-Trap® to study the relationship between structural properties of biomolecular condensates and their fusion times. They found that fusion times, an indicator of condensate density, varies depending on their structural organization. The findings highlight how physical…

j.yeh27 August 2020

Blog posts

Electrostatic effects on vimentin stiffness demonstrated with the C-Trap^®

A recently published study from the lab of Prof. Sarah Köster at the University of Göttingen investigated how electrostatic conditions influence the mechanical properties of intermediate filament vimentin, such as structural stability. The researchers assessed these features by stretching the protein in different buffer conditions, using the C-Trap® with correlated optical…

j.yeh6 August 2020

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