Protein folding

Blog posts

New application note shows how to study transient conformational changes of kinases using the C-Trap^®

We are excited to announce that our latest application note, Real-time detection of kinase conformational changes in the presence of a small-molecule inhibitor, is available to download. The application note is perfect for protein research, as it showcases how you can use the C-Trap® Optical Tweezers – Fluorescence & Label-free…

j.yeh17 September 2020

Blog posts

Study shows how chaperone enzyme ClpB processively translocates polypeptide loops using C-Trap^® correlated optical tweezers and confocal microscopy

A new study published in Nature reports how researchers verified the intricate process of disaggregating entangled proteins by analyzing chaperone enzyme ClpB at a single-molecule level. The C-Trap® correlated optical tweezers and confocal microscopy enabled them to analyze how the member of the Hsp100 chaperone family translocates looped polypeptide substrates…

j.yeh13 February 2020

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Blog posts

C-Trap^® installed at Technical University of Munich

We are happy to announce the recent installation of the C-Trap® at the Technical University of Munich, Germany, in the lab of Prof. Matthias Rief. The installed C-Trap combines optical tweezers with 2-color fluorescence microscopy and will be used by students and postdocs in the Rief lab. Among other areas,…

j.yeh11 February 2020

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