C-Trap

Blog posts

C-Trap^® installed at Rockefeller University

LUMICKS is proud to announce that a C-Trap® optical tweezers-fluorescence microscopy system was installed at Rockefeller University in the Liu Lab led by Assistant Professor Shixin Liu. Dr. Liu wil use the C-Trap to study how cells execute replication, transcription, translation and degradation processes in a coordinated manner, and how environmental changes…

Jerom Langeveld14 December 2016

Blog posts

Optical Tweezers-Fluorescence Microscopy Workshop at LUMICKS HQ

From November 15th to the 17th, LUMICKS organized a correlative optical tweezers-fluorescence microscopy workshop in our office in Amsterdam. It proved to be a great success! Seven participants joined us in the hands-on workshop, with lectures from prof. Gijs Wuite, prof. Erwin Peterman and Roeland van Wijk, and were updated…

Jerom Langeveld23 November 2016

max-planck-institute-molecular-cell-biology-genetics

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Customer Case Story MPI-CBG Dresden

In March 2016 LUMICKS delivered a C-Trap® correlative optical tweezers - fluorescence microscopy instrument to the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden. The instrument was acquired at the end of 2015 by a group of MPI-CBG principle investigators to fulfill a need for application…

Jerom Langeveld15 November 2016

Blog posts

STED Application Note Now Online

Today’s quantitative analysis of DNA-protein interactions at the single-molecule level requires the capability of measuring under biologically relevant conditions with high temporal resolution. This problem can especially be observed when in vitro experiments are linked with the in vivo situation in which proteins interact highly dynamic with DNA at high…

Jerom Langeveld1 November 2016

optical-tweezers-fluorescence-microscopy-groningen

Blog posts

C-Trap^® Installation at University of Groningen

LUMICKS is proud to announce that we successfully installed a C-Trap® at the University of Groningen in the lab of professor Roos. The Roos group will use the optical tweezers-fluorescence microscopy system to investigate the structure and mechanics of viral capsids and their interaction with host cell molecules. We’re looking…

Jerom Langeveld26 October 2016

de-ingenieur-newsitem-optical-tweezers-fluorescence-microscopy

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LUMICKS Featured in De Ingenieur

LUMICKS has been featured in the Dutch magazine De Ingenieur with an article named “Bewegend DNA-beeld”, or a moving DNA-image. De Ingenieur is a monthly Dutch magazine that specializes in technological developments and the policies surrounding them. This month’s edition is focused on medical biology, with a four-page article by…

Jerom Langeveld12 October 2016

Blog posts

Interactions between Single Fibrin Fibers are Measured for the First Time

Cells and tissue change their structural properties to cope with large strains e.g. caused by blood flow and external stress. Understanding microstructural remodeling of the extracellular matrix requires knowledge of biological events down to the smallest scale. One of the mechanisms involved in this process is the formation of fibrin…

Jerom Langeveld20 September 2016

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Paper Using LUMICKS Technology Published in Nature

Great news: Another paper using LUMICKS technology was published, this time in Nature! Congratulations to the authors. Several are now part of LUMICKS. In the study “Sliding sleeves of XRCC4-XLF bridge DNA and connect fragments of broken DNA” Brouwer et al. describe how XRCC4 and XLF proteins play a crucial role…

Jerom Langeveld21 July 2016

optical-tweezers-fluorescence-microscopy-Nature-Communications

Blog posts

Study using CTFM Published in Nature Communications

A new paper using the correlative optical tweezers-fluorescence microscopy (CTFM) technology has recently been published in Nature Communications. King, Peterman & Wuite show in "Unravelling the structural plasticity of stretched DNA under torsional constraint" that in torsionally constraint DNA concomitant basepair melting and helical unwinding can occur at forces >~50…

Jerom Langeveld15 June 2016

correlative-optical-tweezers-fluorescence-microscopy-system

Blog posts

Two More C-Trap^® Systems are Ready for Shipment

Last week the assembly of two new C-Trap® systems was finished. We are really excited about the experiments the new users will be performing on the correlative optical tweezers and fluorescence microscopy system. Don't want to miss out on LUMICKS' latest news? Follow us now on LinkedIn!

Jerom Langeveld14 June 2016

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