Study using CTFM Published in Nature Communications


A new paper using the correlative optical tweezers-fluorescence microscopy (CTFM) technology has recently been published in Nature Communications. King, Peterman & Wuite show in “Unravelling the structural plasticity of stretched DNA under torsional constraint” that in torsionally constraint DNA concomitant basepair melting and helical unwinding can occur at forces >~50 pN. They also show that an overwound DNA-structure is created at forces >~110 pN. Read the full study here.

Click here for more information about the CTFM technology and what it can do for your research.

Jerom Langeveld

Jerom Langeveld

15 June 2016May 24th, 2017

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