max-planck-institute-molecular-cell-biology-geneticsUncategorised

Customer Case Story MPI-CBG Dresden

In March 2016 LUMICKS delivered a C-Trap® correlative optical tweezers - fluorescence microscopy instrument to the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden. The instrument was acquired at the end of 2015 by a group of MPI-CBG principle investigators to fulfill a need for application…
Jerom Langeveld
15 November 2016
Uncategorised

STED Application Note Now Online

Today’s quantitative analysis of DNA-protein interactions at the single-molecule level requires the capability of measuring under biologically relevant conditions with high temporal resolution. This problem can especially be observed when in vitro experiments are linked with the in vivo situation in which proteins interact highly dynamic with DNA at high…
Jerom Langeveld
1 November 2016
optical-tweezers-fluorescence-microscopy-groningenUncategorised

C-Trap® Installation at University of Groningen

LUMICKS is proud to announce that we successfully installed a C-Trap® at the University of Groningen in the lab of professor Roos. The Roos group will use the optical tweezers-fluorescence microscopy system to investigate the structure and mechanics of viral capsids and their interaction with host cell molecules. We’re looking…
Jerom Langeveld
26 October 2016
de-ingenieur-newsitem-optical-tweezers-fluorescence-microscopyUncategorised

LUMICKS Featured in De Ingenieur

LUMICKS has been featured in the Dutch magazine De Ingenieur with an article named “Bewegend DNA-beeld”, or a moving DNA-image. De Ingenieur is a monthly Dutch magazine that specializes in technological developments and the policies surrounding them. This month’s edition is focused on medical biology, with a four-page article by…
Jerom Langeveld
12 October 2016
DNA-repair-NatureUncategorised

Paper Using LUMICKS Technology Published in Nature

Great news: Another paper using LUMICKS technology was published, this time in Nature! Congratulations to the authors. Several are now part of LUMICKS. In the study “Sliding sleeves of XRCC4-XLF bridge DNA and connect fragments of broken DNA” Brouwer et al. describe how XRCC4 and XLF proteins play a crucial role…
Jerom Langeveld
21 July 2016
optical-tweezers-fluorescence-microscopy-Nature-CommunicationsUncategorised

Study using CTFM Published in Nature Communications

A new paper using the correlative optical tweezers-fluorescence microscopy (CTFM) technology has recently been published in Nature Communications. King, Peterman & Wuite show in "Unravelling the structural plasticity of stretched DNA under torsional constraint" that in torsionally constraint DNA concomitant basepair melting and helical unwinding can occur at forces >~50…
Jerom Langeveld
15 June 2016
optical-tweezers-workshopUncategorised

CTFM Workshop at BIOCEV a Great Success

The latest workshop on correlative optical tweezers and fluorescence microscopy (CTFM) was a great success. On June 8 and 9 the participants joined the hands-on workshop and were updated on the latest developments on CTFM at BIOCEV in Prague. Interested in attending the next workshop? Register now on our workshop…
Jerom Langeveld
10 June 2016

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