Article Archives - Page 2 of 4 - LUMICKS

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LUMICKS Featured in Cambridge Independent

This week’s issue of Cambridge Independent featured an article about our partnership with AstraZeneca and the University of Cambridge! We are proud to see the field of dynamic single-molecule analysis reaching a new milestone once again. This brings us closer to our goal: improving human health by providing unparalleled insight…
Jerom Langeveld
23 July 2018
optical tweezers dna repair force extension manipulation visualization RAD51 RecombinationUncategorised

Investigation of the Interaction of RAD51 with ssDNA Using CTFM and X-ray Crystallography

Recently, the paper “Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA" has been published in The EMBO Journal. Congratulations to Dr. Ineke Brouwer and all co-authors! Brouwer et al. combined Correlative Optical Tweezers-Fluorescence Microscopy (CTFM) with X-ray crystallography to investigate the function of human RAD51…
Jerom Langeveld
20 March 2018
Gijs & Erwin VU MagazineUncategorised

LUMICKS co-founding Professors G. Wuite & E. Peterman in the media after winning the NWO Physics Valorisation Prize 2017

After being awarded the NWO Physics Valorisation Prize 2017 for the valorization of their single-molecule research, Prof. Gijs Wuite and Prof. Erwin Peterman are featured in an article published in VU Magazine and an interview on a famous Dutch radio station (both in Dutch). The article showcases who these top biophysicists are,…
Jerom Langeveld
27 February 2018
strand-displacement polymerization investigated with u-Flux microfluidics microfluidics laminar flow cellUncategorised

Strand-Displacement Polymerization by Reverse Transcriptase Investigated using LUMICKS’ u-Flux™

The journal Nucleic Acids Research has recently published the paper "Pausing kinetics dominates strand-displacement polymerization by reverse transcriptase". We would like to congratulate the authors! Malik et al. (2017) used optical tweezers and, among other technologies, microfluidics to study the enzymatic activity of the murine leukemia Virus reverse transcriptase (RT). RT catalyzes the formation of an integration-competent double-stranded DNA…
Jerom Langeveld
26 September 2017
C-Trap Chemical Reviews AFS Biochemical Society TransactionsUncategorised

C-Trap® and AFS™ systems mentioned in two review articles

We are proud to announce that two review articles refer to LUMICKS; one highlighting the C-Trap® Optical Tweezers-Fluorescence Microscopy system and the other one specifying the AFS™ Acoustic Force Spectroscopy system.  Norregaard et al. (2017) reviews relevant theoretical tools to analyze data obtained from single-molecule experiments performed in intracellular environments and describes state-of-the art visualization techniques…
Jerom Langeveld
6 July 2017
Top banner image was licensed by Daniel Schwen / Wikimedia Commons.Uncategorised

New C-Trap® acquired by the University of Göttingen

A new C-Trap® system has recently been acquired by the Georg August University in Göttingen, Germany. The C-Trap® was successfully installed in the lab of the “Nanoscale Imaging of Cellular Dynamics” research group, led by Prof. Dr. Sarah Köster, at the Institute for X-Ray Physics. The optical tweezers-fluorescence microscopy system will be…
Jerom Langeveld
7 June 2017
optical tweezers dna repair force extension manipulation visualization RAD51 RecombinationUncategorised

Investigation of the Role of RAD52-DNA Complex in DNA Repair Using Optical Tweezers CTFM and Microfluidics

The article “Human RAD52 Captures and Holds DNA Strands, Increases DNA flexibility, and Prevents Melting of Duplex DNA: Implications for DNA Recombination” was recently published in Cell Reports. Congratulations to Dr. Ineke Brouwer and all co-authors! In this paper optical tweezers coupled with fluorescence microscopy and microfluidics were used to investigate…
Jerom Langeveld
24 March 2017

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