News – Page 17

Blog posts

Single-Molecule Workshops at the Rockefeller University and LUMICKS Amsterdam

During the end of October, we organized two single-molecule workshops at the Rockefeller University, NY, and our headquarters in Amsterdam. The participants in Amsterdam had the great opportunity to attend an inspiring lecture given by Prof. Mattias Rief (Technical University of Munich), while Dr. Michael Wasserman (Rockefeller University) and Dr. Arne Gennerich…

Jerom Langeveld2 November 2018

Blog posts

New C-Trap™ Installed at the University at Buffalo

LUMICKS successfully installed a C-Trap® optical tweezers–fluorescence microscopy system in the lab of Assistant Professor Priya Banerjee at the University at Buffalo. The group of Dr. Banerjee will use the C-Trap to investigate the structural dynamics and phase behavior of intrinsically disordered proteins (IDPs). IDPs are characterized by conformational plasticity and structural heterogeneity,…

Jerom Langeveld17 October 2018

structure, function and dynamics interplay of RNA molecules

Blog posts

Deciphering the structure-function relationship of RNA: a complete guide

The interplay between dynamics, structure, and function of many RNA molecules is tied to essential biological processes, such as the regulation of gene expression and protein synthesis. However, modern imaging and biochemical methods often fail in explaining these relations. This application note is a complete guide on how to resolve the structure-function relationship…

Jerom Langeveld10 October 2018

Blog posts

The 2018 Nobel Prize in Physics

The winners of the 2018 Nobel Prize in Physics. Niklas Elmehed/© Nobel Media AB 2018 Congratulations to the winners of the 2018 Nobel Prize in Physics: Arthur Ashkin, Gérard Mourou and Donna Strickland for their pioneering work on lasers. Among them, Arthur Ashkin was recognized for developing the first optical tweezers. We…

Jerom Langeveld3 October 2018

Blog posts

Single-Molecule Workshop at the University of Cambridge

An engaging single-molecule workshop organized by LUMICKS took place at the University of Cambridge. During the workshop, the participants performed state-of-the-art experiments to examine DNA-protein interactions and DNA mechanics in real-time and at the single-molecule level, using the C-Trap® optical tweezers - fluorescence microscopy system. Next to the practical sessions, Matt Newton, a researcher from…

Jerom Langeveld2 October 2018

Blog posts

Unraveling the Kinetics and Strength of T Cell Adhesion to Fibronecting using z-Movi^®;

A new study in Cell Reports shows the first results obtained using z-Movi; ! Kamsma et al. used the z-Movi to measure the adhesion forces and kinetics of CD4+ T lymphocytes (CD4) to fibronectin in living conditions. They then investigated how these properties are influenced by interleukin-7 (IL-7), the main regulatory cytokine of CD4 cells. The results…

Jerom Langeveld2 October 2018

Leiden c-trap installation Alireza Mashaghi Lab

Blog posts

C-Trap™ installed at Leiden University

LUMICKS is happy to announce that a new C-Trap™ optical tweezers is now housed in the lab of Dr. Alireza Mashaghi at Leiden University, the Netherlands. Dr. Mashaghi’s group will use the C-Trap to perform single-molecule experiments and investigate molecular folding processes. In particular, the group aims to understand how chaperones reshape…

2 October 2018

Blog posts

LUMICKS Featured in Cambridge Independent

This week’s issue of Cambridge Independent featured an article about our partnership with AstraZeneca and the University of Cambridge! We are proud to see the field of dynamic single-molecule analysis reaching a new milestone once again. This brings us closer to our goal: improving human health by providing unparalleled insight…

Jerom Langeveld23 July 2018

Measure Cell Mechanics with Acoustic Force Spectroscopy

Blog posts

Novel Method for Single-Cell Mechanical Probing using LUMICKS’ AFS™ System

The article ‘Probing cellular mechanics with Acoustic Force Spectroscopy’ has recently been published in the journal Molecular Biology of the Cell. Congratulations to all the authors on their inspiring research! Undergoing deformations plays a vital role in the function of Red Blood Cells (RBCs) and could be used as a biomarker,…

Jerom Langeveld10 July 2018

Department of Biochemistry, University of Cambridge

Press releases

New Centre of Excellence in Dynamic Single-Molecule Analysis for Accelerated Drug Discovery in collaboration with AstraZeneca and the University of Cambridge

The center will be based around LUMICKS’ C-Trap® optical tweezers–fluorescence microscope, which for the first time enables real-time observation and probing of biomolecular interactions. The approach will be pioneered in several pharmacology and biology assays with the aim of accelerating the discovery of potential new drugs.