Blog posts

Blog posts

Two papers give new insights on protein droplets using LUMICKS’ C-Trap™

Two new papers published at Physical Review Letters and Nature Communications give new insights on protein droplets. Congratulations to all the authors! Jawerth et al. developed a method to investigate the frequency-dependent rheology and surface tension of protein droplets. They used the C-Trap™ optical tweezers – fluorescence microscope to trap…

j.yeh31 May 2019

Blog posts

C-Trap^® SR installed at the National Institutes of Health (NIH)

A new C-Trap® SR was installed at the National Institutes of Health, Maryland, USA, in the labs of Prof. Antonina Roll-Mecak and Prof. Keir Neuman. The LUMICKS optical tweezers-STED nanoscopy system allows the user to visualize molecular interactions with super-resolution microscopy. The highly interdisciplinary group of Prof. Roll-Mecak works on unraveling the chemical and genetic complexity of the microtubule cytoskeleton, or "the tubulin code". The…

Jerom Langeveld14 May 2019

Single-Molecule Workshop at ShanghaiTech

Blog posts

Dynamic Single-Molecule Workshop at the ShanghaiTech University

The first dynamic single-molecule workshop of the year just came to an end! Last week, 16 participants got to experience the C-Trap® Optical Tweezers – Fluorescence Microscope to investigate DNA mechanics and do experiments using their own samples. Additionally, the workshop included lectures from Prof. Bo Sun, during which he discussed his…

j.yeh26 April 2019

Blog posts

C-Trap™ SR installed at Northeastern University

We are happy to have installed a C-Trap® SR, our optical tweezers-STED nanoscope, in shared lab space for an interdisciplinary group led by Prof. Mark Williams at Northeastern University, in Massachusetts, USA. The lab of Prof. Williams is highly regarded as one of the leaders of single-molecule analysis, making us even more proud of this installation. The lab focuses…

j.yeh16 April 2019

C-Trap installation at Sun Yat-sen University, China

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C-Trap™ installed at Sun Yat-sen University, China

School of Physics at the Sun Yat-sen University, China, is now equipped with a C-Trap™ Optical Tweezers-Fluorescence Microscope. This advanced instrument is believed to be able to boost up a variety of exciting researches in SYSU, such as DNA/RNA mechanics and protein-DNA or -RNA interactions during DNA replication, transcription, and repair that Prof.…

j.yeh8 April 2019

Blog posts

AFS™ installed at University of Göttingen

An AFS™ system was installed in the lab of Professor Andreas Janshoff at the Department of Biophysical Chemistry at the University of Göttingen, Germany. Together with the team of Professor Claudia Steinem (Institute for Organic and Biomolecular Chemistry), the Janshoff group will use it to investigate the properties of and…

j.yeh4 April 2019

C-Trap installation at B CUBE TU Dresden

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Second C-Trap™ installed in Dresden, Germany

The city of Dresden, Germany, is now the home of two C-Trap® systems! The latest installation took place at the Center for Molecular and Cellular Bioengineering at TU Dresden, where the instrument became part of the Joint Technology Platform. Being operated in the "Molecular Imaging and Manipulation" facility, the system will be available to multiple…

j.yeh26 March 2019

AFS installation at Victor Chang Cardiac Research Institute, Australia

Blog posts

First AFS™ installed in Australia

The very first AFS™ Acoustic Force Spectroscopy-system in Australia has been successfully installed in the lab of Prof. Boris Martinac at the Victor Chang Cardiac Research Institute. Prof. Martinac and his team conduct research on cellular transduction processes associated with mechanosensitive ion channels. Although it has been shown that dysfunction of these ion channels contributes…

j.yeh12 March 2019

Blog posts

New insights into Cas9 off-target activity

The paper “DNA stretching induces Cas9 off-target binding and cleavage” was just published in Nature Structural and Molecular Biology. Congratulations to all the authors! In this paper, scientists at the MRC London Institute of Medical Sciences and AstraZeneca studied how CRISPR-Cas9 differentiates between on-targets and off-targets. They used the C-Trap®…

j.yeh8 March 2019

Blog posts

Step into the unresolved with the Surface Assay Toolkit

During BPS19, we introduced the Surface Assay Toolkit! A unique assortment of new features that enable scientists to investigate the cytoskeleton from a whole new dynamic perspective. The Surface Assay Toolkit brings together the C-Trap™ and m-Trap™ optical tweezers with: Label-free surface imaging using IRM; Rapid fluorescent imaging in solution using Widefield; Fluorescence surface imaging using TIRF; High throughput experimental workflow at the surface. Download the 2019…

j.yeh7 March 2019

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