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Protein folding Application Note Now Online

The biological function of many macromolecules such as proteins and RNA are tightly coupled to their conformation and their conformational dynamic. The correct folding of a protein into its native state is essential for its biological function. Misfolded or unfolded proteins are known to be either (partially) inactive or to…
Jerom Langeveld
7 February 2017
C-Trap® Installed at ShanghaiTech UniversityBlog posts

C-Trap® Installed at ShanghaiTech University

LUMICKS is very excited to announce the first C-Trap® installation in Asia. The C-Trap® was installed at the lab of Assistant Professor Bo Sun at ShanghaiTech University in Shanghai, China. The group of Dr. Sun will use the C-Trap® to do a multitude of experiments involving DNA-protein interactions. His research…
Jerom Langeveld
6 February 2017
optical-tweezers-fibrin-fibersBlog posts

Effect of Mechanical Stress on Individual Vimentin Filaments Studied using the C-Trap®

The paper "Nonlinear Loading-Rate-Dependent Force Response of Individual Vimentin Intermediate Filaments to Applied Strain" using LUMICKS’ C-Trap® has recently been published in Physical Review Letters. Congratulations to all the authors! The study led by Prof. Sarah Köster, investigated the mechanical properties of the cytoskeleton in eukaryotic cells; and more specifically…
Jerom Langeveld
27 January 2017
Young Startup Award LUMICKSBlog posts

LUMICKS Wins Young Startup Award

LUMICKS won this year’s national Dutch Young Startup Award! The Young Startup Award is awarded to innovative companies in the Netherlands that are seen to have strong technological developments with an international impact. It is great to get the conformation that LUMICKS is on the right track to make a lasting impact…
Jerom Langeveld
24 January 2017
Blog posts

C-Trap® installed at Rockefeller University

LUMICKS is proud to announce that a C-Trap® optical tweezers-fluorescence microscopy system was installed at Rockefeller University in the Liu Lab led by Assistant Professor Shixin Liu. Dr. Liu wil use the C-Trap to study how cells execute replication, transcription, translation and degradation processes in a coordinated manner, and how environmental changes…
Jerom Langeveld
14 December 2016
optical-tweezers-fluorescence-microscopy-amolfBlog posts

C-Trap® Installed at FOM Institute AMOLF

LUMICKS is happy to announce another C-Trap® installation in the Netherlands: at FOM Institute AMOLF in the Tans Biophysics lab led by Professor Sander Tans. Prof. Tans will use the C-Trap® to study the mechanisms by which chaperones act to achieve native protein folds. A recent paper in Nature (see also…
Jerom Langeveld
28 November 2016
max-planck-institute-molecular-cell-biology-geneticsBlog posts

Customer Case Story MPI-CBG Dresden

In March 2016 LUMICKS delivered a C-Trap® correlative optical tweezers - fluorescence microscopy instrument to the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden. The instrument was acquired at the end of 2015 by a group of MPI-CBG principle investigators to fulfill a need for application…
Jerom Langeveld
15 November 2016
Blog posts

STED Application Note Now Online

Today’s quantitative analysis of DNA-protein interactions at the single-molecule level requires the capability of measuring under biologically relevant conditions with high temporal resolution. This problem can especially be observed when in vitro experiments are linked with the in vivo situation in which proteins interact highly dynamic with DNA at high…
Jerom Langeveld
1 November 2016
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