j.yeh

LUMICKS Continues Efforts to Offset CO2 Emissions Generated by Global Travel by Planting Trees on Former Farmland

In 2019, LUMICKS employees flew across the world to connect and collaborate with customers. To combat the unavoidable emissions their travel generated, the company sponsored the planting of 5,500 trees on former farmland. Over the next 30 years, those trees are expected to capture 1-1.5 times the CO2 emissions of…

j.yeh16 June 2021

Blog posts

C-Trap^® reveals how HP1α-mediated heterochromatin modulates its stability in response to applied forces

In a recent publication by Keenen et al. in eLife, the authors uncover the biophysical properties of heterochromatin protein 1α (HP1α) and present a new model on how it mediates DNA condensation and phase separation. Employing a combination of ensemble and single-molecule assays, they found that within phase-separated HP1α-DNA condensates,…

j.yeh9 June 2021

Press releases

Regensburg Center for Interventional Immunology adopts LUMICKS’ z-Movi^® Cell Avidity Analyzer

In its effort to develop effective cellular immunotherapies for cancer treatment, the Regensburg Center for Interventional Immunology (RCI) in Germany has purchased LUMICKS’ z-Movi®. The placement highlights the promise of measuring cell avidity between immune cells and their tumor targets to improve the selection of CARs and accelerate the development…

j.yeh26 May 2021

Blog posts

New insights into the dynamics of initial replisome assembly uncovered by the C-Trap^®

In a recent article published in Nature Communications, Sanchez et al. successfully employed LUMICKS’ C-Trap® to discover new insights into the molecular dynamics of initial replisome formation. In a collaborative effort between Prof. Dekker (TU Delft) and Prof. Diffley (Francis Crick Institute) laboratories, the scientists uncovered that origin recognition complex…

j.yeh18 May 2021

Press releases

LUMICKS to return COVID-related relief funding to Dutch and US governments

LUMICKS, a leading next generation life science tools company renowned for its innovative platforms for Dynamic Single-Molecule and Cell Avidity analysis, announces that it has made the decision to return the COVID-related relief funding it received in both the Netherlands and the United States. During 2020, LUMICKS received a total…

j.yeh18 May 2021

Blog posts

Three C-Trap^® systems installed in the US East Coast

We are excited to share that three more institutes on the US East Coast are now equipped with a C-Trap® Optical Tweezers – Fluorescence Microscope! The three new instruments are now housed at a new core facility at MSKCC, at the NanoSystems Laboratory at the OSU, and at the UPMC-Hillman Cancer…

j.yeh17 May 2021

Press releases

LUMICKS Raises $93 Million in Series D Financing

Backed by global investor syndicate led by new investors Farallon Capital Management and Lauxera Capital Partners along with Softbank Fund 2, funds and accounts advised by T. Rowe Price Associates, Parian Global Management, Gilde Healthcare, Pura Vida Investments, and Irving Investors. Amsterdam, the Netherlands – April 16, 2021 – LUMICKS,…

j.yeh15 April 2021

Blog posts

Highly reproducible single-molecule analysis of transient structures of native proteins using m-Trap^® dual optical tweezers combined with Raman spectroscopy

A recent publication by Dai et al. in Nature Communications presents an optical tweezers-coupled Raman spectroscopy platform providing tuneable and reproducible surface-enhanced Raman spectroscopy (SERS) measurements. By combining a Raman microscope with the dual-trap optical tweezers and microfluidic flow chamber of the m-Trap®, the scientists were able to characterize three…

j.yeh8 April 2021

ROS activation in macrophages optical tweezers fluorescence microscopy

Blog posts

Early activation of single macrophages captured by the C-Trap^®

In a recent article published in Small Methods, researchers reveal a method that uniquely captures the early phase of oxidative stress response in macrophages. Employing the powerful combination of optical tweezers, confocal fluorescent microscopy, and microfluidics of the C-Trap®, they measured the real-time intracellular response of individual macrophages to a…

j.yeh11 March 2021

Blog posts

Researchers identify KIF1A properties associated with neuron transport with the C-Trap^®

A recent article in Journal of Cell Biology (JCB) describes how researchers at Albert Einstein College of Medicine measured the force-generating properties of KIF1A, a kinesin-3 motor known to transport synaptic vesicle precursors in neurons. Using the C-Trap® optical tweezers and motility assays, the researchers identified the mechanical properties of…

j.yeh25 February 2021

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