A recent study by Szu‐Ning Lin et al. for the first time provided direct information on the dynamics of the interaction between HU and DNA and how this interaction is influenced by ionic conditions and DNA conformation.
j.yeh9 November 2021
A recent publication by Losito et al. from the lab of Prof. David Rueda (Imperial College London), reveals new information on the kinetics and mechanism of Cas12a-DNA interaction.
j.yeh13 October 2021
We are pleased to announce two key appointments to our Board of Directors that bring a combined 40 years of executive-level experience in human resources and finance. Melissa McLaughlin and Solange Glaize are the newest addition to LUMICKS Board, each offering invaluable insight that will help pave the way for…
j.yeh30 September 2021
A recent publication by Kucera et al. in Nature Communications combined TIRF assays and Optical Tweezers measurements to investigate myosin-independent actin contraction that is relevant during cytokinesis and cell division. The authors found a new mechanism showing how anillin, a non-motor actin crosslinking and scaffolding protein, substitutes for the activity…
j.yeh23 August 2021
We are pleased to announce the appointment of Dr. Paul Wheeler to its leadership team, effective July 1, 2021. In the newly-created position of Chief Commercial Officer, Dr. Wheeler will lead LUMICKS aggressive commercial growth strategy by building a stronger market presence, developing highly-effective sales teams, and focusing on enhanced…
j.yeh17 August 2021
We're proud to announce ithe installation of a C-Trap® Optical Tweezers – Fluorescence & Label-free Microscopy system at VIB, the life sciences research institute in Flanders, Belgium. The C-Trap will support the research efforts of six VIB research groups across three Belgian universities studying processes underlying neurodegenerative disorders.
j.yeh28 July 2021
INmune Bio is employing the z-Movi® cell avidity analysis platform to demonstrate that the mechanism of action of the tumor-priming is the increase in NK cell:tumor cell avidity. Early data acquired by the z-Movi® support their hypothesis that increased cell avidity enhances NK cell killing of tumor cells. This allows…
j.yeh22 July 2021
In a recent article published in Science Advances, researchers investigated the mechanical consequences of a missense mutation within a highly conserved region, P305L, in the kinesin motor family member A1 (KIF1A). By employing a single-molecule approach using the C-Trap® as well as biochemical and genetic assays, Lam et al. found…
j.yeh15 July 2021
A recent article published in the Journal of Physical Chemistry Letters provides insight into the stability and folding dynamics of RNA G-quadruplexes (RG4). Using the C-Trap® optical tweezers, Ye et al. investigated the influence of a proximal single-stranded (ss) RNA sequence and found that its existence significantly impairs RG4 stability.…
j.yeh24 June 2021
