j.yeh

New Nature Paper Relies on LUMICKS’ C-Trap^® Technology to Understand Functionality of Key Protein Involved with Incorrect DNA Repair of Dangerous Lesions Linked to Cancer Predisposition

C-Trap® technology was used in new research designed to understand the function of a key protein involved in DSB) repair. DSB repair is fundamental in maintaining the genome integrity and when compromised can lead to cancer predisposition.

j.yeh15 February 2022

Maria Themeli, Amsterdam AMC, T cell sensitivity and persistence, blood cancers, z-Movi, Cell Avidity analysis

Press releases

New study published in Translational Medicine highlights cell avidity’s power as a functional biomarker for improved CAR-T design in preventing tumor escape

Using cell avidity measurements and traditional immuno-assays, the researchers successfully demonstrated that co-expression of costimulatory receptors along with an FDA approved BCMA and CD19 CAR can improve both durability of potential treatments as well as persistence for common blood cancers.

j.yeh23 January 2022

Press releases

LUMICKS Announces the Installation of its Quadruple C-Trap^® Instrument at Rockefeller University to Expand Fundamental Research of DNA Processes

The C-Trap will support the research of Prof. Michael O’Donnell to investigate the mechanisms of DNA replication. Between O’Donnell and his collaborator Prof Shixin Liu, Rockefeller University will use the C-Trap to unveil the mechanisms of many types of enzymes, such as multi-protein DNA replicating machines of bacteria and eukaryotes.

j.yeh11 January 2022

Press releases

LUMICKS Announces Adoption of z-Movi® Cell Avidity Analyzer by Two Major Centres for Cancer Immunology

LUMICKS announced today that two major centers of excellence in cancer immunology, Fred Hutchinson Cancer Research Center and Oxford University, have adopted the z-Movi Cell Avidity Analyzer instrument for the development of promising immunotherapeutic strategies.

j.yeh10 January 2022

Blog posts

C-Trap^® experiments contribute to elucidating the role of the helicase HELQ in different mechanisms of DNA repair

A recent paper published in Nature by the group of Dr. Simon Boulton from the Francis Crick Institute enlightens the role played by the helicase HELQ in the context of DNA repair. The researchers took advantage of the combination of microfluidics, optical tweezers, and fluorescence microscopy of the C-Trap® to…

j.yeh23 December 2021

Press releases

LUMICKS Welcomes World-Renowned Scientists and Business Executives to Scientific Advisory Board

We are pleased to announce key appointments to our Scientific Advisory Board, with both new members strategically selected to help support our growth strategy.

j.yeh15 December 2021

Blog posts

ZAP-S binding prevents the refolding of SARS-CoV-2 RNA, inhibits programmed ribosomal frameshifting

A new Nature Communications article sheds light into the mechanisms that govern programmed ribosomal frameshifting (PRF) in SARS-CoV-2 virus, as demonstrated by C-Trap experiments.

j.yeh13 December 2021

Blog posts

ParB sliding to non-specific DNA regions visualized using C-Trap^®

A recent work published in eLife by Francisco de Asis Balaguer et al. shed light on the interaction of ParB with DNA, the consequent DNA condensation, and the role of cytidine triphosphate (CTP) in this process – at a single-molecule level. Using the C-Trap® the researchers investigated the role of…

j.yeh30 November 2021

Top banner image was licensed by Sergey Novikov / Shutterstock.com

Blog posts

Experienced C-Trap^® users in Munich, Germany, acquired second system

The Technical University of Munich, Germany, is now the home of two C-Trap® Optical Tweezers – Fluorescence Microscopes. With this second installation, the renowned lab of Prof. Matthias Rief is taking their dynamic single-molecule research to the next level. Prof. Rief is a pioneer in studying processes involved in protein…

j.yeh24 November 2021

Press releases

LUMICKS Announces New Additions to its Executive Management Team

Jos Maas joins as new general manager of Dynamic Single Molecule business and Geerte Hesen joins as new General Counsel. They both bring strong managerial acumen and a track record of supporting innovation.

j.yeh17 November 2021

Join our newsletter