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Single-molecule​ Workshop at the ShanghaiTech UniversityBlog posts

Single-Molecule Workshop at the ShanghaiTech University

On April 9 to 11, a successful Single-molecule workshop took place in the lab of Prof. Bo Sun at the ShanghaiTech University, organized by LUMICKS. During the practical hands-on workshop, the participants conducted state-of-the-art single-molecule experiments in the fields of DNA mechanics, repair, and molecular motors. They also had the chance to…
Jerom Langeveld
30 April 2018
optical tweezers dna repair force extension manipulation visualization RAD51 RecombinationBlog posts

Investigation of the Interaction of RAD51 with ssDNA Using CTFM and X-ray Crystallography

Recently, the paper “Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA" has been published in The EMBO Journal. Congratulations to Dr. Ineke Brouwer and all co-authors! Brouwer et al. combined Correlative Optical Tweezers-Fluorescence Microscopy (CTFM) with X-ray crystallography to investigate the function of human RAD51…
Jerom Langeveld
20 March 2018
C-Trap® installed at Ludwig Maximilian UniversityBlog posts

C-Trap™ installed at Ludwig Maximilian University

LUMICKS recently installed a new C-Trap® system in the lab of Dr. Johannes Stigler at the Ludwig Maximilian University of Munich, Germany. Dr. Stigler and his group will use the C-Trap® to study the structure and organization of chromosomes. Their goal is to determine the processes leading to the three-dimensional folding of chromosomes, which have…
Jerom Langeveld
5 March 2018
C-Trap AFS G2 Brochure coverBlog posts

Introducing New Generation of Dynamic Single-Molecule Analysis Instruments

At the BPS18 meeting, LUMICKS will introduce its latest product generation of the C-Trap™ optical tweezers-fluorescence microscopy and AFS™ parallel single-molecule force spectroscopy instruments. The new G2 generation represents an evolution of our original instruments, bringing new enabling features, improved performance, and automation. These new developments allow dynamic biomolecular processes to be studied in…
Jerom Langeveld
16 February 2018
Motor Protein Application NoteBlog posts

Motor Protein Application Note Now Online

The cytoskeleton and its many molecular motors are major players in a variety of cellular functions. The interconnected networks of cytoskeletal filaments act as tracks directing molecular motor transport and provide structural support and organization to cells. One example of a class of motor proteins is the myosin superfamily, a…
Jerom Langeveld
10 January 2018
https://lumicks.com/wp-content/uploads/m-Trap_BoSun_installation_closeup-313x146.pngBlog posts

m-Trap® installed at ShanghaiTech University

LUMICKS is thrilled to announce the first m-Trap® installation at ShanghaiTech University in Shanghai, just a month after the launch of our landmark high-resolution optical tweezers system. Assistant Professor Bo Sun acquired the m-Trap within a year after a C-Trap® was installed in his lab. Dr. Sun believes that conventional ensemble techniques are often not sufficient…
Jerom Langeveld
8 January 2018
Acoustic Force Spectroscopy Protein Unfolding Application Note high throughputBlog posts

AFS™ installed at University of Münster

LUMICKS is very proud to announce the latest AFS™ Stand-Alone installation at the University of Münster in the lab of Professor Timo Betz. The group has an outstanding expertise in investigating the dynamics and mechanical properties of different cell types with various biophysical approaches. Their goal is to understand the underlying principles and how these are…
Jerom Langeveld
22 December 2017
C-Trap® installed at Imperial College LondonBlog posts

C-Trap™ installed at Imperial College London

Recently, LUMICKS successfully installed a new C-Trap® optical tweezers-fluorescence microscopy system in the lab of Professor David Rueda at the Imperial College London, England, whose lab also features an AFS™ system for high throughput measurements. The group of Prof. Rueda develops and uses quantitative single-molecule approaches to investigate mechanisms underlying complex biological processes. These…
Jerom Langeveld
18 December 2017
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