Chenlu Yu

Blog posts

Deciphering the Dynamic Mechanisms of Thymine DNA Glycosylase (TDG) in DNA Repair

Explore our latest blog post on thymine DNA glycosylase (TDG), where we delve into groundbreaking research using single-molecule assays to understand TDG’s crucial role in DNA repair. Discover how these insights could lead to advanced therapeutic strategies.

Chenlu Yu5 December 2024

Blog posts

Shu Complex: A New Frontier in DNA Repair and Cancer Therapy

Explore the groundbreaking research on the Shu Complex and its role in enhancing RAD51-mediated DNA repair. Discover how this vital mechanism can be a new target in cancer therapy and the innovative methods used in DNA repair studies.

Chenlu Yu22 November 2024

Blog posts

Revealing MeCP2 Mechanism: Single-Molecule Insights into Epigenetic Regulation in Neurodevelopmental Disorders

Explore the dynamic mechanism of MeCP2 in gene expression regulation, its complex interactions with DNA, and implications for Rett syndrome. This research brief uncovers groundbreaking research using single-molecule methods to understand MeCP2’s impact on disease pathology and potential therapeutic targets.

Chenlu Yu24 October 2024

Press releases

Dutch Life Science Tools LUMICKS secures €20 million from European Investment Bank to accelerate drug discovery for cancer

Amsterdam-based LUMICKS signs €20 million venture debt with EIB to accelerate the development and launch of its new product, designed to advance immunotherapy development for cancer research. LUMICKS’ next generation high-throughput cell avidity platform aims to transform the drug discovery process by replacing traditional screening methods, expediting development for life-saving…

Chenlu Yu10 October 2024

Blog posts

DNA Polymerase Undergoes Rapid Exchange and Retains Memory at Replication Forks

Explore groundbreaking research on DNA polymerase exchange dynamics using the innovative C-Trap technology. Learn how this study offers new insights into DNA replication, polymerase activity, and the dynamic nature of the replisome. Ideal for both scientists and biotechnology professionals.

Chenlu Yu28 August 2024

Blog posts

Key mechanism in Fanconi Anemia pathway discovered with the C-Trap

Explore groundbreaking research on the FANCD2-I complex, central to the Fanconi anemia pathway, and its newly discovered mechanism in DNA repair and replication fork protection. This deep dive details the latest insights from recent studies, elucidating the complex's role in genomic stability and potential implications for cancer therapy.

Chenlu Yu1 August 2024

Blog posts

Chromatin remodeling dynamics revealed at the single-molecule level in a recent pioneering study

Explore groundbreaking research on chromatin remodeling dynamics using the C-Trap, revealing 'hopping' and 'sliding' mechanisms of chromatin remodelers on DNA. Gain insights into the push-pull model and its implications for gene regulation and genomic integrity. Dive into the latest advancements in genomic research.

Chenlu Yu30 May 2024

Press releases

LUMICKS Appoints Hugo de Wit as CEO and Executive Board Director

Life Sciences Veteran Joins To Accelerate Company Growth Amsterdam, the Netherlands – May 29, 2024 – LUMICKS, a leading life science tools company that develops instruments for dynamic single-molecule and cell avidity analysis, today announced that Hugo de Wit has been appointed Chief Executive Officer, based in the Company’s headquarters…

Chenlu Yu29 May 2024

DNA repair pathwya via PARP1-DNA co-condensation

Blog posts

Securing Broken DNA Ends: PARP1’s Vital Role in Co-Condensation with DNA

Explore how PARP1's involvement in DNA repair through condensate formation secures genetic integrity. Read this blog to understand the dynamics of DNA repair processes in real-time.

Chenlu Yu19 March 2024