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viral assembly Archives - LUMICKS

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Single-molecule measurements with AFS® and optical tweezers reveal progressive assembly of viruses

The research lab of Dr. Gijs Wuite in the Netherlands recently published a single-molecule study in Science Advances, demonstrating the progressive self-assembly steps of viruses. Methods, such as optical tweezers and acoustic force spectroscopy (AFS®), enabled the researchers to study the transient and otherwise hard-to-verify steps associated with viral assembly.…
Santiago Gisler
14 May 2020
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New study evaluates the dynamics behind viral assembly at the single-molecule level using both C-Trap™ and AFS®

Researchers used the C-Trap™ optical tweezers – fluorescence microscopy system and acoustic force spectroscopy (AFS) to study the processes underlying viral assembly. The study evaluated the capsid formation and DNA condensation of virus-like particles (VLPs) at the single-molecule level and in real time. The results serve to expand our understanding…
Santiago Gisler
22 August 2019