Andrea Candelli

Key takeaways Researchers have examined how format-tuning bispecific T cell engagers (BTEs) boosts therapeutic efficacy against clear cell renal cell carcinoma (ccRCC). Using a novel persistent multivalent T cell engager (PMTE) to enhance cell avidity and tumor targeting, they tackle challenges like low plasma half-life, poor tumor retention, and antigen…

This is a summary of: Arellano-Ballestero, H., Zubiak, A., Dally, C., Orchard, K., Alrubayyi, A., Charalambous, X., Michael, M., Torrance, R., Eales, T., Das, K., Tran, M. G. B., Sabry, M., Peppa, D., & Lowdell, M. W. (2024).Proteomic and phenotypic characteristics of memory-like natural killer cells for cancer immunotherapy.Journal for…