The group has an outstanding expertise in investigating the dynamics and mechanical properties of different cell types with various biophysical approaches. Their goal is to understand the underlying principles and how these are related to cellular function and development.
The AFS technology will be used to study the elastic properties of endothelial and epithelial cells by obtaining force-deformation curves in a highly parallel manner. In the framework of the DFG excellence cluster “Cells in Motion”, results from these studies will eventually help understanding how function, signaling and the dynamics of cells are correlated to their mechanical properties. This, in turn, can be utilized to better understand and thus tackle certain kinds of diseases.
This is the first time that our AFS technology is applied in quantitative rheological measurements of cells. We wish Prof. Betz and his team success with their research, and hope the AFS will contribute to achieving their goal!