
SMBio 2025
Dresden
Single molecules. Joint research.
The SMBio single-molecule biology symposium is a 2-day event, bringing together scientists interested in single-molecule approaches to biology from all over the world to share their research, connect, and exchange ideas and experiences.
Date: 17 – 18 March 2025
Location: Max-Planck-Institute of Molecular Cell Biology and Genetics (MPI-CBG) Dresden, Germany
Registrations are now closed.
Keynote speakers

Stephan Grill
MPI-CBG Dresden

Iddo Heller
VU Amsterdam
Speakers
Michael Schlierf
BCUBE/TU Dresden, Germany
Ingrid Tessmer
University of Würzburg, Germany
Neva Caliskan
University of Regensburg, Germany
Beat Fierz
EPFL Lausanne, Switzerland
Marcus Jahnel
TU Dresden, Germany
Alexander von Appen
MPI-CBG Dresden, Germany
Dagmar Klostermeier
University of Münster, Germany
Georg Krainer
University of Graz, Austria
Michal Wieczorek
ETH Zürich, Switzerland
Lennart Randau
Philipps University of Marburg, Germany
Richard Boerner
Hochschule Mittweida, Germany
Anita Jannasch
University of Tübingen, Germany
Jan-Philipp Günther
University of Zürich, Switzerland
Dina Grohmann
University of Regensburg, Germany
Timon Andre
EMBL Heidelberg, Germany
Agenda
Join us to meet world industry leaders and inspiring speakers to explore how dynamic single-molecule analysis will shape the world of tomorrow.
Day 1 – Monday 17 March
12:30-13:00 | Registration and welcome coffee |
13:00-13:45 | Welcome and keynote talk by Stephan Grill – “Protein condensation on and with DNA” |
13:45-14:45 |
Scientific Session #1: Neva Caliskan – “Single-molecule studies of viral regulatory RNA structures and interactions” Richard Boerner – “smFRET-guided integrative modelling of ncRNA: from single structures to a structural ensemble: Georg Krainer – “Single-molecule microfluidics for protein analysis and biomarker sensing” Anita Jannasch – “Superpower behavior of the budding yeast kinesin-8” |
15:10-15:40 | Coffee and snacks |
15:40-16:40 |
Scientific Session #2: Michael Schlierf – “Molecular mechanisms of the bacterial integron revealed with single molecule biophysics” Dagmar Klostermeier – “A single-molecule FRET study of protein/protein interface stability in DNA topoisomerases” Jan-Phillipp Günther – “Single-Molecule Studies of NEIL1 Diffusion on DNA” |
16:40-17:00 | Introducing LUMICKS: Unlocking measurements of forces and interactions in biology |
17:00-17:30 | Poster Flash Talks + Closing remarks |
17:30-19:00 | Posters and bites and beers |
19:15 | Transfer to Dresden Old Town |
20:00 – 21:30 | Social event |
Day 2 – Tuesday 18 March
8:30-9:00 | Welcome coffee |
9:00-9:45 | Welcome and keynote talk by Iddo Heller |
9:45-11:10 |
Scientific Session #3: Ingrid Tessmer – “Mechanistic insights into DNA alkylation damage repair” Marcus Jahnel – “RNAs under tension: folding and misfolding in the age of condensates” Lennart Randau – “Visualization of DNA targeting by type IV CRISPR-Cas systems” Michal Wieczorek – “Function and regulation of microtubule-nucleating complexes” |
11:10-11:40 | Coffee and snacks |
11:40-13:00 |
Scientific Session #4: Alexander von Appen – “A self-enforcing protein-DNA surface hydrogel safeguard nuclear integrity.” Dina Grohmann – “DNA origami-based single-molecule force spectroscopy advances the molecular understanding of transcription initiation” Timon Andre – “Biophysical and structural characterization of the human Pol I pre-initiation complex” Beat Fierz – “Decoding PTM Signaling from Chromatin to the Cytoskeleton on the Single-Molecule Level” |
13:00-13:10 | Closing remarks |
13:10-14:00 | Optional lunch in canteen |
14:00 onwards |
Optional program: 14:00 – 15:30 | Feedback session for C-Trap users with the LUMICKS team 14:00 – 16:30 | Try out the C-Trap: Demo session |

Register Now
Registrations are now closed.