In this application note, we highlight multiple experiments conducted at Banerjee Lab at the University at Buffalo, and Hyman Lab at the Max Planck Institute of Molecular Cell Biology and Genetics on phase separation using the C-Trap dynamic single molecule technology. We present the two approaches the studies used to assess specific properties of protein droplets through applied forces, namely:
1. Droplet Fusion, and
2. Microrheology and Viscocity.
Manipulate and study protein droplet dynamic and properties in realtime to understand phase separation
Dr. Priya Banerjee Associate Professor of Biophysics at University at Buffalo
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