Cell avidity measurement: a new accurate method to predict in vivo CAR T cell efficacy and minimize drug discovery timelines

Title
Cell avidity measurement: a new accurate method to predict in vivo CAR T cell efficacy and minimize drug discovery timelines
Reading time
15 min
Collaborators
Dr. Marcela Maus Associate Professor at Harvard Medical School and Director of Cellular Immunotherapy at Massachusetts General Hospital
Topics

Cell Avidity

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In this application note, we describe the power of cell avidity in the search for improved CAR T cell therapies. We report on two publications from the lab of Dr. Marcela V. Maus (Harvard Medical School) that illustrate how cell avidity measurement with the z-Movi Cell Avidity Analyzer can accelerate the CAR T cell therapy development process against cancer by:

1. Enabling fast and reproducible assessment of CAR T cell therapy in vivo efficacy
2. Allowing quick selection of CAR T cell candidates earlier
3. Leading to faster more accurate CAR T cell drug discovery
Title
Cell avidity measurement: a new accurate method to predict in vivo CAR T cell efficacy and minimize drug discovery timelines
Reading time
15 min
Collaborators
Dr. Marcela Maus Associate Professor at Harvard Medical School and Director of Cellular Immunotherapy at Massachusetts General Hospital
Topics

Cell Avidity

Download now

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