Single-Molecule Biology Symposium 2024
The Single-Molecule Biology Symposium is a 2-day event, bringing together scientists interested in single-molecule approaches to biology from all over the world to share their research, connect, and exchange ideas and experiences.
Date: 17-18 October 2024
Location: Kellen Biolink at the Rockefeller University New York, NY
Keynote speakers
Luis Aragón
MRC Laboratory of Medical Sciences
London, UK
Probing SMC Complexes and Top2 Activity on DNA: Insights from Single-Molecule Optical Tweezers
Agata Smogorzewska
The Rockefeller University
New York, USA
RTF2: Mechanisms of Function in DNA Replication and Replication Stress Response
Tim Lohman
Washington University
St. Louis, USA
Dynamics of translocases and helicases on DNA.
James Berger
Johns Hopkins School of Medicine
Baltimore, USA
Using the LUMICKS C-Trap to reassess how bacterial replicative helicases load and translocate on DNA
Speakers
Arne Gennerich
Albert Einstein College of Medicine, New York, USA
Kinesin-14 HSET and KlpA are non-processive microtubule motors with load-dependent power strokes
Micah McCauley
Northeastern University, Boston, USA
Kinetics and Energetics of Nuclear Chaperones
Yukun Wang
Rockefeller University, New York, USA
Unveiling the regulatory role of human elongation factors in RNA Polymerase II transcription with single-molecule resolution
Laura Finzi
Emory College, Atlanta, USA
Macromolecular crowders: Influencers of DNA Topology
Ayush Mistry
Saint Louis University, St. Louis, USA
Rad52 sorts and stacks Rad51 at the 5′ DNA junction to drive nucleoprotein filament formation in Homologous Recombination
Shannon Yan
Stanford University, Stanford, USA
Talk title tba
Thomas Germe
University of Colorado, Anschutz, USA
A structural role for Topoisomerase II in resolving telomere entanglements in late anaphase
Keir Neuman
National Institute of Health, Bethesda, USA
Direct observation of type IA topoisomerase conformational dynamics
Xuebiao Yao
University of Science and Technology of China, Hefei, China
Talk title tba
Sarah Hengel
TUFTS University, Medford, USA
The Shu complex, an exciting new RAD51 and RPA modulator
Matthew Schaich
University of Pittsburgh, USA
Nucleosome unwrapping and PARP1 conformation drive affinities for chromatin and DNA breaks
Yongli Zhang
Yale University, New Haven, USA
Energetics and kinetics of SNARE assembly revealed by optical tweezers
Vitaly Klyachko
Washington University, St. Louis, USA
Single-molecule imaging revealed nanoscale organization and metabolic plasticity of synaptic transmission
Agenda
Join us to meet world industry leaders and inspiring speakers to explore how dynamic single-molecule analysis will shape the world of tomorrow.
Day 1 – Thursday 17 October
| 12:00 PM | Welcome & Registration |
| 1:00 PM | Introduction |
| 1:20 PM | Keynote Session 1 Tim Lohmann Agata Smogorzewska |
| 2:40 PM | Break |
| 3:00 PM | Scientific Talk Session 1 Sarah Hengel Keir Neumann Yongli Zhang |
| 4:15 PM | Break |
| 4:35 PM | Scientific Talk Session 2 Xuebiao Yao Laura Finzi Thomas Germe (Poster talk) Ayush Mistry (Poster talk) Matthew Schaich |
| 6:15 PM | Break and depart for dinner & social |
Day 2 – Friday 18 October
| 8:00 AM | Welcome / Coffee & pastries |
| 9:00 AM | Kickoff / Introduction Day 2 |
| 9:10 AM | Keynote Session 2 Luis Aragon James Berger |
| 10:30AM | Poster Session & Coffee |
| 12:30 PM | Lunch |
| 1:30 PM | Group photo |
| 1:50 PM | Scientific Talk Session 3 Yukun Wang Arne Gennerich Vitaly Klyachko |
| 3:05 PM | Break |
| 3:40 PM | Scientific Talk Session 4 Micah McCauley Shannon Yan |
| 4:30 PM | Closing Remarks |
| 5:00 PM | Departure |
94% of previous attendees said that they would participate again:
“Excellent meeting!”
“I felt this was over too soon!”
“A great mix of interesting research and helpful advice.”
Apply now for a seat to join the Single-Molecule Biology Symposium 2024!
Closing date: 1 October 2024
*Due to limited spots, we strongly encourage a maximum of 2 participants per lab, to ensure that everyone has a chance to attend!
