Join us at the BPS Conference in Philadelphia on February 10-14, 2024! Our team at LUMICKS will be there to explain the C-Trap which is the world’s first instrument that allows simultaneous manipulation and visualization of single-molecule interactions in real-time.
Join our presentation
Trey Simpson, PhD
Principal Scientist at LUMICKS
PRESENTATION TITLE
Accelerating Biological Discovery: An Automated, End-to-End Solution in Single-Molecule Research
DATE & TIME
Monday, February 12, 3:30pm – 5:00pm
LOCATION
Room 103C
PRESENTATION DESCRIPTION
Dynamic single-molecule research has revolutionized our understanding of biology by providing crucial insights into key molecular and cellular mechanisms, such as DNA repair and phase separation processes, among others.
However, this field of science has traditionally been accessible only to experts capable of building and operating complex home-built instruments, able to produce specific DNA or protein samples, and developing sophisticated algorithms for correct single-molecule data analysis and interpretation.
To democratize access to single-molecule technologies, LUMICKS C-Trap was introduced as the first instrument of its kind. LUMICKS C-Trap uniquely combines optical tweezers, single-molecule fluorescence, and automated microfluidics, allowing the correlation of single-molecule force and fluorescence measurements in real time to enable the investigation of dynamic molecular mechanisms with a ready-to-go instrument.
Here, we will unveil our latest advancements in creating a comprehensive end-to-end solution designed to transform the field of dynamic single-molecule research: from a vast range of DNA and protein samples to the full automation for instrument set-up and experiment execution, all the way to a seamless data analysis and interpretation.
GUEST SPEAKER
Gabriella Chua
The Rockefeller University
PRESENTATION TITLE
Single-molecule visualization of genome navigation by genetic and epigenetic machinery
GUEST SPEAKER
Brittani Schnable
University of Pittsburgh
PRESENTATION TITLE
Thymine DNA glycosylase combines sliding and hopping to efficiently search for 5-formylcytosine
GUEST SPEAKER
Jee Min Kim
NIH National Cancer Institute
PRESENTATION TITLE
Pushing and pulling nucleosomes: unraveling chromatin remodeler dynamics using C-Trap
Visit our posters
POSTER TITLE
Unparalleled approaches to directly visualize DNA-Binding proteins and biomolecular condensates
SESSION
DNA replication, recombination, and repair
POSTER BOARD
B168
DATE
Sunday, Feb 11 2024 at 1:45PM
LOCATION
Exhibit Hall AB
POSTER TITLE
An efficient biochemistry platform to incorporate replication forks, DNA lesions and nucleosome arrays to single-molecule experiments
SESSION
DNA replication, recombination, and repair
POSTER BOARD
B163
DATE
Sunday, Feb 11 2024 at 1:45PM
LOCATION
Exhibit Hall AB
