Single-Molecule Job Board

Academic, research and science jobs in the single-molecule field

Open Positions

PhD position | Haifa, Israel

The Kaplan Lab has several openings for students interested in a PhD in experimental single-molecule biophysics.
Physics students: The position involves design and construction of an advanced optical setup combining optical manipulation and fluorescence detection, and its use to characterize the interplay between chromatin dynamics and gene expression.
Biology students: The position combining molecular biology and high resolution, single-molecule optical tweezers to study the interactions between transcription factors, polymerases, and chromatin.

The lab is a highly interdisciplinary one, and students can expect to acquire a wide set of skills during their studies. The Technion – Israel Institute of Technology is located in the beautiful city of Haifa, on the Mediterranean coast.

Some recent works from the lab:

Rudnizky et. al., PNAS (2019),
Zananbiri et. al., eLife (2019),
Rudnizky et. al., Nature Communications (2016)

PhD position | Groningen, the Netherlands

The Single Molecule Biochemistry group led by Dr. Katarzyna Tych, is looking for students with backgrounds in biochemistry, physics, engineering, computer science or any other related fields who are motivated to work in an interdisciplinary research environment studying the structure-function relationships of proteins on the single molecule level.  You will have access to a C-Trap optical tweezer setup equipped with three-color fluorescence detection and will receive full training in the use of the instrument. Application is open until 29 March 11.59pm / before 30 March 2020 Dutch local time (CET).

Post doc | Delft, the Netherlands

In the context of a new initiative to strengthen collaborations between TU Delft and ErasmusMC, Gijsje Konderink’s Biological Soft Matter lab at TU Delft has a postdoc position available in the area of mechanobiology and cartilage repair. This project joins expertise in soft matter physics of tissues (TU Delft) and in regenerative medicine (collaborators at Erasmus MC) towards the aim of generating tissue-mimetic hydrogels for human disease models and tissue regeneration. The postdoc in the Delft group will focus on making and characterizing tissue-mimetic gels and studying cell-gel mechanobiology; at the same time, a postdoc in the Erasmus MC group will focus on stem cell differentiation, cartilage repair, and an osteoarthritis-in-a-dish model. In collaboration with neighboring groups, we will also explore applications for neuronal and liver tissue.

Post doc | Atlanta, GA, USA

The Finzi-Dunlap lab and the C-Trap facility at Emory University seek a motivated experimentalist to study transcriptional regulation, and supervise the use of the new NSF/Emory-sponsored C-Trap microscope from LUMICKS which combines optical tweezers, single-molecule fluorescence detection, and microfluidics. The position is a unique opportunity to do cutting edge research and collaborate with a variety of exceptional investigators.

Phd Studentiship | King’s College London

A 4-year BBSRC studentship at King’s College London is open. The objective of the program will be to dissect the molecular determinants that govern the mechanical properties of the nuclear envelope within individual cells and isolated nuclei using optical tweezers coupled with light microscopy. The successful candidate will be working at the interface between physical sciences, biological sciences, and chemistry, in the labs of Pof. Sergi Garcia-Manyes, Prof. Ulrike Eggert and in close collaboration with LUMICKS.

Faculty Position | Galveston, TX, USA

The University of Texas Medical Branch (UTMB Health), Galveston, Texas, seeks an outstanding faculty candidate for a tenure-track/tenured position at the rank of Assistant, Associate or Full Professor in the field of Single Molecule Biophysics in the Department of Biochemistry and Molecular Biology. The ideal candidate will have extensive experience in using magnetic or optical tweezers, super resolution light or atomic force microscopy, to address molecular mechanisms of important biomedical problems. A very attractive recruitment package of salary, start-up funding and newly renovated space will be offered.

Post doc | Delft, the Netherlands

We have an opening for a postdoctoral researcher in the exciting area of understanding the mechanisms of eukaryotic replication at the single-molecule level. This project provides you the unique opportunity to work with reconstituted eukaryotic systems and to explore their functioning from a quantitative mechanistic point of view. Candidates should have experience in biophysics or quantitative biochemistry.

Please send your cover letter with motivation, full CV, and the names and contact information of three references to Prof. Nynke Dekker at n.h.dekker ‘at’

Post-doc | Chicago, IL, USA

The Zhou lab at the University of Illinois Chicago is recruiting a postdoc with experience in single-molecule instruments. Our lab is equipped with an advanced optical-tweezer instrument from LUMICKS. We are interested in a wide range of studies on intrinsically disordered proteins, including binding kinetics, conformations and dynamics under macromolecular crowding, and physical properties of protein droplets formed by liquid-liquid phase separation. To apply, please send CV and names of three references to

Post-doc | Leiden, the Netherlands

Leiden University invites applications for a post-doctoral fellow in the Faculty of Science, at the Mashaghi lab. The postdoctoral fellow will design and perform single-molecule experiments to understand biomolecular folding processes. The ideal candidate will have a Ph.D. in physics (experimental and/or theoretical) or engineering with a strong publication record. The Mashaghi lab is a part of the Leiden Academic Centre for Drug Research (LACDR), one of Europe’s premier drug research institutes. The lab is involved in interdisciplinary research at the interface of physics, engineering, and biomedicine.

Please inquire at

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