C-Trap™ installed at University of Vermont

We are happy to announce the recent installation of the C-Trap™ at the University of Vermont Larner College of Medicine. Several labs will use the correlated optical tweezers – fluorescence microscopy instrument to investigate the dynamics of molecular machines that interact with … Read More

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C-Trap Albert Einstein College of Medicine

C-Trap™ installed at Albert Einstein College of Medicine

We are happy to announce the installation of the C-Trap™ at the Albert Einstein College of Medicine in New York in the lab of Prof. Dr. Arne Gennerich. The instrument combines optical tweezers with 3-color total internal reflection fluorescence (TIRF; … Continue Reading

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New application note shows how to study Cas9 target specificity at the single-molecule level using the C-Trap™

We are happy to announce that our application note Analyze Cas9 Binding and Cleavage Properties in Real Time while Manipulating DNA Structures is available to download on our website. In this application note, you can learn how the group of … Continue Reading

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Study establishes molecular forces responsible for condensation of ribonucleoprotein-RNA complexes

Researchers investigated the molecular driving forces underlying the condensation and decondensation of ribonucleoproteins using the C-Trap™. Specifically, they showed that sequence-dependent features of the RNA and ribonucleoprotein molecules partially dictate phase transitions. These findings can help scientists further understand the … Continue Reading

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AFS

New study maps internal and external structures of red blood cell aggregates by combining AFS™ and 3D imaging

Researchers used acoustic force spectroscopy (AFS™) in combination with 3D imaging to induce clustering and rotation of red blood cells, enabling them to study the properties of cell aggregates. The new approach, which is based on radiation and stream forces, … Continue Reading

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New study evaluates the dynamics behind viral assembly at the single-molecule level using both C-Trap™ and AFS™

Researchers used the C-Trap™ optical tweezers – fluorescence microscopy system and acoustic force spectroscopy (AFS) to study the processes underlying viral assembly. The study evaluated the capsid formation and DNA condensation of virus-like particles (VLPs) at the single-molecule level and … Continue Reading

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First Dynamic Single-Molecule Summer School in China!

Yet another premiere! LUMICKS organized the very first Dynamic Single-Molecule Summer School at Tsinghua University in Beijing. During the three-day event, nineteen participants received in-depth training in both the theory and practice of dynamic single-molecule (DSM) techniques. Our application scientists dedicated … Read More

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New study resolves helicase dynamics and interactions during DNA replication using C-Trap™

Researchers from Rockefeller University used a C-Trap™ optical tweezers – fluorescence microscopy system to observe the behavior of the main component of the replisome – the eukaryotic CMG helicase – during DNA replication. The study offers exciting new insights into … Read More

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Application note describing the use of C-Trap to study cell mechanics and functions available for downloading

We are happy to announce that our latest application note “Manipulating and Studying Cellular Mechanics and Functions in Real Time” is available to download on our website. In this application note, you can read how we, together with three different … Read More

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C-Trap™ & AFS™ installed at Tianjin University

LUMICKS is proud that Tianjin University, China, is now equipped with both a C-Trap™ Optical Tweezers-Fluorescence Microscopy and AFS™ Parallel Single-Molecule Force Spectroscopy. The systems are installed in the State Key Laboratory of Precision Measurement Technology and Instruments. Both systems will contribute to … Read More

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