Unparalleled resolution, Unlimited applications
Ultimate Core Facility System
Unparalleled resolution, Unlimited applications
Ultimate Core Facility System
Unparalleled resolution, Unlimited applications
Ultimate Core Facility System
Today’s scientific trends are racing towards smaller scales and experimentation that provides both structural and mechanistic insights. To decipher biomolecular mechanisms, you need methods capable of detecting the interactions between biomolecules as they happen and at the single-molecule level.
Whereas single-molecule techniques used to be restricted to the realm of physicists, their application in biological systems has long been proved that can aid the researcher answer the most impactful questions in Molecular Biology. Our instruments have been developed by taking this into account to enable all life scientists use this technology and answer novel scientific questions.
The C-Trap® is the world’s first instrument that allows simultaneous manipulation and visualization of single-molecule interactions in real time. This enables you to study processes at the single-molecule level from multiple angles, providing an unparalleled, broad perspective on biomolecular interactions — quickly and effectively
How disease-causing proteins interact with DNA and how drugs affect these processes or block their action? In which way do proteins change DNA architecture? With the C-Trap you can uncover the structure, function, and dynamic interplay between proteins and nucleic acids by looking at their behavior in real time and at the single-molecule level.
How do proteins fold, and which are the players that cause them to misfold? What are the intermediate states that constitute a proteins’ energy landscape, and how does the ribosome or chaperones modulate it? Perform dynamical studies to investigate a protein’s exact folding mechanisms in real time.
How do motor proteins transport cellular cargo through filaments? How fast do they move, and what are the parameters that influence their activity? How do single filaments interact with each other, and whatare their mechanical properties? The C-Trap provides you with detailed information about these associated networks and processes at high resolution.
Similar to the phase separation observed upon mixing vinegar and oil, biomolecules, such as proteins and RNAs, can compartmentalize into membrane-less droplets. Manipulate these dynamic structures with optical tweezers to study how changes the phase of matter of biomolecular condensates may influence cell functions.
With the ever-increasing pressure to produce breakthrough discoveries in the least amount of time, researchers need an instrument that brings unprecedented insights into different biological mechanisms with high precision, accuracy, and reliability fast.
With the ever-increasing pressure to produce breakthrough discoveries in the least amount of time, researchers need an instrument that brings unprecedented insights into different biological mechanisms with high precision, accuracy, and reliability fast.
Choose and combine from a variety of imaging methods and different optical trap configurations designed specifically to solve the needs of different experimental designs.
Multicolor confocal, perfect for visualizing biological processes in solution.
The perfect choice for performing experiments in highly crowded environments, offering unprecedented resolution (< 35 nm).
Image biomolecular processes with low protein concentration in solution with high acquisition rates.
Suitable for visualization on surfaces as it eliminates background fluorescence outside the focal plane.
IRM allows you to visualize microtubules without the need for fluorescence labeling.
For highly stable surface assays
For your typical assay in solution
Excellent for complex interactions
Choose and combine from a variety of imaging methods and different optical trap configurations designed specifically to solve the needs of different experimental designs.
Multicolor confocal, perfect for visualizing biological processes in solution.
The perfect choice for performing experiments in highly crowded environments, offering unprecedented resolution (< 35 nm).
Image biomolecular processes with low protein concentration in solution with high acquisition rates.
Suitable for visualization on surfaces as it eliminates background fluorescence outside the focal plane.
IRM allows you to visualize microtubules without the need for fluorescence labeling.
For highly stable surface assays
For your typical assay in solution
Excellent for complex interactions
LUMICKS offers accessible, fast, and more reproducible than ever dynamic single-molecule (DSM) research – from sample to publication
LUMICKS offers the best possible support for your research needs. We team up with you to realize your institutes projects by demonstrating the scientific impact of the C-Trap and generating data for your users.
Our application scientists constantly travel to present seminars and perform demonstrations to different institutes around the globe. We enable the interest of all potential users by organizing different events, such as seminars, workshops, and demonstrations, and meeting with PIs individually to understand their research needs and design their research proposals.
Furthermore, we are often organizing practical hands-on workshops on Optical Tweezers– Fluorescence & Label-free Microscopy technology. In these events, participants explore different state-of-the-art single-molecule applications and perform hands-on experiments to visualize molecular interactions, measure protein activity, and study single-molecule mechanics, in real-time, with a sub-nm and sub-pN resolution. The workshops include “test your own sample” sessions, enabling the user to see their biomolecule of interest in action and often get preliminary data.
Throughout our history, we have supported multiple successful grants, varying in the amount of funding and users involved. Our application scientists are experienced in highlighting the unique value of correlated optical tweezers with fluorescence and label-free microscopy, and generating unique preliminary to prove this value.
Our goal is to minimize your time to results, ensure success, and provide a C-Trap instrument that is easy to use and maintain. To this end we have a dedicated team, proving user training, applications support, and system checkups as part of our collaboration, and dedication to the superior quality of our instrument and support as detailed below.
After installation of the new C-Trap, a LUMICKS scientist provides a three-day operator training that enables the users to operate all modes of the instrument and to set up experiments autonomously.
We also provide personalized support at later stages, e.g., when new people join the lab. Then, a LUMICKS specialist comes to your lab and gives dedicated training based on your specific needs.
Acquiring a LUMICKS instrument guarantees access to premium expertise with our application specialists and service support. We stand by you to deliver unparalleled performance through the life of your instrument. Most importantly, we pride ourselves in delivering a worry-free system with unlimited software updates and remote support.
LUMICKS will provide you with our standard full one-year warranty. The system will stay in factory specifications during this time, and include a system service at the end of the year. After the lapse of the warranty, we provide extensions in the form of three different attractive packages to offer our continued support.
Users can get in contact with our support scientists and engineers via phone or our website for no additional costs. Users will find numerous resources at help.lumicks.com and we will be available to discuss experimental design and data analysis.