News – Page 9 – LUMICKS

LUMICKS Raises $93 Million in Series D Financing

Backed by global investor syndicate led by new investors Farallon Capital Management and Lauxera Capital Partners along with Softbank Fund 2, funds and accounts advised by T. Rowe Price Associates, Parian Global Management, Gilde Healthcare, Pura Vida Investments, and Irving Investors. Amsterdam, the Netherlands – April 16, 2021 – LUMICKS,…

j.yeh15 April 2021

Blog posts

Highly reproducible single-molecule analysis of transient structures of native proteins using m-Trap^® dual optical tweezers combined with Raman spectroscopy

A recent publication by Dai et al. in Nature Communications presents an optical tweezers-coupled Raman spectroscopy platform providing tuneable and reproducible surface-enhanced Raman spectroscopy (SERS) measurements. By combining a Raman microscope with the dual-trap optical tweezers and microfluidic flow chamber of the m-Trap®, the scientists were able to characterize three…

j.yeh8 April 2021

Blog posts

Measure interaction strength between target cell and TCR T-cell in HPV-related cancers with the z-Movi^®

In a recent review article in Immunology, Fakhr et al. presented the z-Movi® Cell Avidity Analyzer as a solution to characterize T-cell populations by measuring the binding strength between immune and cancer cells using non-invasive acoustic force. Binding events between a T-cell and its target cell determine the initiation of…

Adrià Ferragut26 March 2021

C-Trap® installed at University of Groningen, NL

Blog posts

New C-Trap^® installation at the University of Groningen opens avenues for investigating the conformational cycle of chaperone proteins

We are thrilled to announce the installation of a C-Trap® at the University of Groningen, Netherlands, in the lab of Dr. Katarzyna (Kasia) Tych. The installed C-Trap combines optical tweezers with 3-color fluorescence microscopy, which the team will use to investigate protein stabilities, molecular chaperoning, and conformational regulation. They plan…

Adrià Ferragut23 March 2021

Blog posts

Recent m-Trap^® installation at the University of Liège will unlock new potential in dynamic folding experiments

We are happy to announce the recent installation of the m-Trap® at the University of Liège, Belgium, in the lab of Prof. Dr. Anne-Sophie Duwez. The installed m-Trap will provide her team with ultra-high force resolution and stability for their research in single-molecule mechanical unfolding experiments and the means to…

Adrià Ferragut16 March 2021

ROS activation in macrophages optical tweezers fluorescence microscopy

Blog posts

Early activation of single macrophages captured by the C-Trap^®

In a recent article published in Small Methods, researchers reveal a method that uniquely captures the early phase of oxidative stress response in macrophages. Employing the powerful combination of optical tweezers, confocal fluorescent microscopy, and microfluidics of the C-Trap®, they measured the real-time intracellular response of individual macrophages to a…

j.yeh11 March 2021

Blog posts

Researchers identify KIF1A properties associated with neuron transport with the C-Trap^®

A recent article in Journal of Cell Biology (JCB) describes how researchers at Albert Einstein College of Medicine measured the force-generating properties of KIF1A, a kinesin-3 motor known to transport synaptic vesicle precursors in neurons. Using the C-Trap® optical tweezers and motility assays, the researchers identified the mechanical properties of…

j.yeh25 February 2021

Top banner images were licensed by Jose Luis Stephens (Santiago de Chile) / Sean Pavone (Salt Lake City) / Boris Stroujko (Wurzburg) / f11photo (Tokyo) / Shutterstock.com

Blog posts

LUMICKS technologies installed all around the world

As turbulent 2020 was, we are happy to have managed to install various LUMICKS instruments all around the world. Our dynamic single-molecule instruments enable researchers to analyze complex dynamic details related to the behavior and interaction of single molecules. One of these installations is the newly installed C-Trap® system at the…

j.yeh23 February 2021

Blog posts

New application note shows how to rapidly assess CAR T-cell strategies for multiple myeloma

We are excited to announce that our latest application note, Rapid assessment of CAR T-cell strategies for multiple myeloma with the z-Movi® Cell Avidity Analyzer, is available to download. In this application note, we highlight cell avidity and in vivo experiments performed in collaboration with the teams of Dr. Eric Smith (Dana-Farber Cancer Institute) and…

j.yeh16 February 2021

Blog posts

The softening effect of vimentin filament phosphorylation measured with the C-Trap^®

A recent study published in the journal Nanoscale shows how post-translational phosphorylation and proteins binding phosphorylated sites regulate the stiffness of vimentin filaments. The researchers combined several analytical approaches and instruments, including the C-Trap® optical tweezers, to define the role of these modifications and interactions on the mechanical properties of vimentin. Apart from contributing…

j.yeh16 February 2021

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