Single-Molecule Workshop at the University of Cambridge

An engaging single-molecule workshop organized by LUMICKS took place at the University of Cambridge. During the workshop, the participants performed state-of-the-art experiments to examine DNA-protein interactions and DNA mechanics in real-time and at the single-molecule level, using the C-Trap™ optical tweezers – fluorescence microscopy system. … Read More

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z-Movi cell-ligand application

Unraveling the Kinetics and Strength of T Cell Adhesion to Fibronecting using z-Movi™

A new study in Cell Reports shows the first results obtained using z-Movi™ ! Kamsma et al. used the z-Movi to measure the adhesion forces and kinetics of CD4+ T lymphocytes (CD4) to fibronectin in living conditions. They then investigated how these properties are influenced by … Continue Reading

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Leiden c-trap installation Alireza Mashaghi Lab

C-Trap™ installed at Leiden University

LUMICKS is happy to announce that a new C-Trap™ optical tweezers is now housed in the lab of Dr. Alireza Mashaghi at Leiden University, the Netherlands. Dr. Mashaghi’s group will use the C-Trap to perform single-molecule experiments and investigate molecular folding processes. … Continue Reading

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Application Note Enzymatic Activity Now Online

Enzymatic Activity and Inhibition Efficiency Application Note Now Online

The characterization of the enzymatic activity of proteins involved in the DNA machinery and the identification of their inhibitors are key for the development of a variety of treatments. It is essential to collect statistically-relevant data, which is typically achieved … Continue Reading

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LUMICKS Featured in Cambridge Independent

This week’s issue of Cambridge Independent featured an article about our partnership with AstraZeneca and the University of Cambridge! We are proud to see the field of dynamic single-molecule analysis reaching a new milestone once again. This brings us closer … Continue Reading

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Measure Cell Mechanics with Acoustic Force Spectroscopy

Novel Method for Single-Cell Mechanical Probing using LUMICKS’ AFS™ System

The article ‘Probing cellular mechanics with Acoustic Force Spectroscopy’ has recently been published in the journal Molecular Biology of the Cell. Congratulations to all the authors on their inspiring research! Undergoing deformations plays a vital role in the function of Red … Continue Reading

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m-Trap™ installed at the Hong Kong University of Science and Technology

LUMICKS is proud to announce the installation of an m-Trap™ at the Hong Kong University of Science and Technology (HKUST) in the lab of Assistant Professor Jinqing Huang. Dr. Huang will be combining the m-Trap™ with Raman Spectroscopy to investigate … Read More

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Protein Filaments

Novel Insights on the Mechanical Properties of IFs using LUMICKS’ Technology

The journal Science Advances has recently published the paper ‘Viscoelastic properties of vimentin originate from nonequilibrium conformational changes’. We would like to congratulate Prof. Dr. Sarah Köster and all co-authors for their great work on intermediate filaments (IFs)! IFs are … Continue Reading

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Single-Molecule Workshop at LUMICKS Amsterdam

During June 4-5, a captivating single-molecule workshop was given at the headquarters of LUMICKS in Amsterdam. Throughout the workshop, the participants were introduced to our second-generation (G2 line) apparatus and got the chance to perform multiple investigations on them. We … Read More

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C-Trap™ installed at Semmelweis University

LUMICKS is proud to announce the installation of a new C-Trap™ optical tweezers-fluorescence microscopy system in the lab of Professor Miklos Kellermayer at the Semmelweis University in Budapest, Hungary. A major focus of Prof. Kellermayer’s lab is in uncovering the molecular mechanics of the … Read More

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