News - Page 2 of 22

C-Trap reveals mechanism of protein-DNA co-condensate formation.

Blog posts

C-Trap^® experiments reveal mechanism of protein-DNA co-condensate formation

In a recent publication in PNAS, researchers from the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) and the Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) shed light on how proteins interact with individual DNA molecules to form co-condensates. Using LUMICKS’ C-Trap®, which combines optical tweezers, confocal microscopy, and…

Rozina Kardakaris16 March 2022

Press releases

LUMICKS Announces 100^th Customer Placement of its C-Trap^® Product

LUMICKS has announced that it has completed installation and training for its 100th customer sale at the MRC-LMB, marking an important milestone in the company’s growth from a start-up in 2015.

Maja Stephan14 March 2022

Blog posts

C-Trap^® experiments reveal how a pioneer transcription factor interacts with DNA to regulate gene expression

Researchers from the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany, led by Stephan W. Grill, have shed light on the physical nature of the interaction between the pioneer transcription factor Klf4 (Krüppel-like factor 4) and DNA. Using the C-Trap®, which combines optical tweezers, confocal microscopy…

Rozina Kardakaris23 February 2022

Press releases

LUMICKS Unveils Groundbreaking New C-Trap^® Product at Biophysical Society Annual Meeting

New product line C-Trap ‘Edge’ adds important capabilities relevant for surface assays, which are of increasing importance in biophysical and biology research.

Maja Stephan18 February 2022

iScience_monocyte mechanics_Alireza-Mashaghi_optical tweezers_acoustic force spectroscopy

Blog posts

Probing monocyte forces with the C-Trap^® and acoustic force spectroscopy reveals CCL2 regulation of monocyte mechanics

In a first-of-its-kind study from Leiden University, Evers et al. have provided insights into the mechanical properties of monocytes – cells crucial in the fight against infection. By combining two of LUMICKS’ single-cell force spectroscopy approaches, C-Trap® optical tweezers and acoustic force spectroscopy (AFS), they were able to determine that…

Rozina Kardakaris16 February 2022

Press releases

New Nature Paper Relies on LUMICKS’ C-Trap^® Technology to Understand Functionality of Key Protein Involved with Incorrect DNA Repair of Dangerous Lesions Linked to Cancer Predisposition

C-Trap® technology was used in new research designed to understand the function of a key protein involved in DSB) repair. DSB repair is fundamental in maintaining the genome integrity and when compromised can lead to cancer predisposition.

Kassandra Barbetsea15 February 2022

Lyon, France by Pedro Szekely / flickr.com

Blog posts

LUMICKS’ C-Trap^® adopted by 8 teams in 3 multidisciplinary labs in France

We are thrilled to announce the recent C-Trap® installation at École Normale Supérieure Lyon, now the first establishment in France to acquire a C-Trap, where it will be utilized by an astonishing 8 teams across 3 departments! The Physics Department (LPENSL), Cell Biology Department (LBMC), and Plant Biology Department (RDP)…

Ron Eliyahoo28 January 2022

Maria Themeli, Amsterdam AMC, T cell sensitivity and persistence, blood cancers, z-Movi, Cell Avidity analysis

Press releases

New study published in Translational Medicine highlights cell avidity’s power as a functional biomarker for improved CAR-T design in preventing tumor escape

Using cell avidity measurements and traditional immuno-assays, the researchers successfully demonstrated that co-expression of costimulatory receptors along with an FDA approved BCMA and CD19 CAR can improve both durability of potential treatments as well as persistence for common blood cancers.

Kassandra Barbetsea23 January 2022

Press releases

LUMICKS Announces the Installation of its Quadruple C-Trap^® Instrument at Rockefeller University to Expand Fundamental Research of DNA Processes

The C-Trap will support the research of Prof. Michael O’Donnell to investigate the mechanisms of DNA replication. Between O’Donnell and his collaborator Prof Shixin Liu, Rockefeller University will use the C-Trap to unveil the mechanisms of many types of enzymes, such as multi-protein DNA replicating machines of bacteria and eukaryotes.

Kassandra Barbetsea11 January 2022

Press releases

LUMICKS Announces Adoption of z-Movi® Cell Avidity Analyzer by Two Major Centres for Cancer Immunology

LUMICKS announced today that two major centers of excellence in cancer immunology, Fred Hutchinson Cancer Research Center and Oxford University, have adopted the z-Movi Cell Avidity Analyzer instrument for the development of promising immunotherapeutic strategies.

Kassandra Barbetsea10 January 2022

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C-Trap^® experiments reveal mechanism of protein-DNA co-condensate formation

LUMICKS Announces 100^th Customer Placement of its C-Trap^® Product

C-Trap^® experiments reveal how a pioneer transcription factor interacts with DNA to regulate gene expression

LUMICKS Unveils Groundbreaking New C-Trap^® Product at Biophysical Society Annual Meeting

Probing monocyte forces with the C-Trap^® and acoustic force spectroscopy reveals CCL2 regulation of monocyte mechanics

New Nature Paper Relies on LUMICKS’ C-Trap^® Technology to Understand Functionality of Key Protein Involved with Incorrect DNA Repair of Dangerous Lesions Linked to Cancer Predisposition

LUMICKS’ C-Trap^® adopted by 8 teams in 3 multidisciplinary labs in France

New study published in Translational Medicine highlights cell avidity’s power as a functional biomarker for improved CAR-T design in preventing tumor escape

LUMICKS Announces the Installation of its Quadruple C-Trap^® Instrument at Rockefeller University to Expand Fundamental Research of DNA Processes

LUMICKS Announces Adoption of z-Movi® Cell Avidity Analyzer by Two Major Centres for Cancer Immunology

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